4O6R

Crystal Structure of a Putative Aldehyde Dehydrogenase from Burkholderia cenocepacia

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004030	molecular_function	aldehyde dehydrogenase [NAD(P)+] activity
A	0016491	molecular_function	oxidoreductase activity
B	0004030	molecular_function	aldehyde dehydrogenase [NAD(P)+] activity
B	0016491	molecular_function	oxidoreductase activity
C	0004030	molecular_function	aldehyde dehydrogenase [NAD(P)+] activity
C	0016491	molecular_function	oxidoreductase activity
D	0004030	molecular_function	aldehyde dehydrogenase [NAD(P)+] activity
D	0016491	molecular_function	oxidoreductase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	15
Details	BINDING SITE FOR RESIDUE AMP A 501

Chain	Residue
A	ILE145
A	GLY225
A	SER226
A	THR229
A	ARG232
A	ILE233
A	HOH902
A	VAL146
A	LYS172
A	GLU175
A	GLY205
A	GLY209
A	GLN210
A	PHE223
A	THR224

---

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE NO3 A 502

Chain	Residue
A	ARG104
A	PHE150
A	HIS275
A	ALA280
A	ILE282
A	LYS440

---

site_id	AC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE EDO A 503

Chain	Residue
A	HOH787
A	HOH905

---

site_id	AC4
Number of Residues	8
Details	BINDING SITE FOR RESIDUE GOL A 504

Chain	Residue
A	ASP263
A	ASN267
A	ARG300
A	HOH732
A	HOH1026
A	HOH1039
A	HOH1135
A	HOH1136

---

site_id	AC5
Number of Residues	8
Details	BINDING SITE FOR RESIDUE NO3 A 505

Chain	Residue
A	VAL126
A	ASP127
A	PHE130
A	TRP475
A	HOH897
C	ARG441
C	VAL442
C	EDO507

---

site_id	AC6
Number of Residues	14
Details	BINDING SITE FOR RESIDUE AMP B 501

Chain	Residue
B	ILE145
B	VAL146
B	LYS172
B	GLU175
B	GLY205
B	GLY209
B	GLN210
B	PHE223
B	THR224
B	GLY225
B	SER226
B	THR229
B	ARG232
B	HOH881

---

site_id	AC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE NO3 B 502

Chain	Residue
B	ARG104
B	PHE150
B	HIS275
B	ALA280
B	ILE282
B	LYS440

---

site_id	AC8
Number of Residues	8
Details	BINDING SITE FOR RESIDUE GOL B 503

Chain	Residue
B	ASP263
B	ASN267
B	ARG300
B	HOH749
B	HOH796
B	HOH1146
B	HOH1147
D	ARG488

---

site_id	AC9
Number of Residues	9
Details	BINDING SITE FOR RESIDUE NO3 B 504

Chain	Residue
B	VAL126
B	ASP127
B	PHE130
B	TRP475
B	HOH941
D	ARG441
D	VAL442
D	ASN443
D	EDO507

---

site_id	BC1
Number of Residues	8
Details	BINDING SITE FOR RESIDUE NO3 C 501

Chain	Residue
A	ARG441
A	VAL442
C	VAL126
C	ASP127
C	PHE130
C	TRP475
C	HOH722
C	HOH819

---

site_id	BC2
Number of Residues	16
Details	BINDING SITE FOR RESIDUE AMP C 502

Chain	Residue
C	HOH1125
C	ILE145
C	VAL146
C	LYS172
C	SER174
C	GLU175
C	GLY205
C	GLY209
C	GLN210
C	PHE223
C	GLY225
C	SER226
C	THR229
C	ARG232
C	HOH895
C	HOH1124

---

site_id	BC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE NO3 C 503

Chain	Residue
C	ARG104
C	PHE150
C	HIS275
C	ALA280
C	ILE282
C	LYS440

---

site_id	BC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO C 504

Chain	Residue
C	LYS372
C	LEU391
C	ARG392
C	HOH871
C	HOH902

---

site_id	BC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO C 505

Chain	Residue
C	ALA374
C	THR375
C	ALA401
C	HOH884

---

site_id	BC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE EDO C 506

Chain	Residue
C	HOH982

---

site_id	BC7
Number of Residues	8
Details	BINDING SITE FOR RESIDUE EDO C 507

Chain	Residue
A	NO3505
C	ARG104
C	LYS440
C	ARG441
C	VAL442
C	HOH733
C	HOH927
C	HOH1086

---

site_id	BC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL C 508

Chain	Residue
A	HOH651
C	ASP263
C	ASN267
C	ARG300
C	HOH838
C	HOH1141

---

site_id	BC9
Number of Residues	9
Details	BINDING SITE FOR RESIDUE NO3 D 501

Chain	Residue
B	ARG441
B	VAL442
B	ASN443
D	VAL126
D	ASP127
D	PHE130
D	TRP475
D	HOH737
D	HOH743

---

site_id	CC1
Number of Residues	18
Details	BINDING SITE FOR RESIDUE AMP D 502

Chain	Residue
D	ILE145
D	VAL146
D	LYS172
D	SER174
D	GLU175
D	GLY205
D	GLY209
D	GLN210
D	PHE223
D	GLY225
D	SER226
D	THR229
D	HOH876
D	HOH1102
D	HOH1114
D	HOH1122
D	HOH1123
D	HOH1124

---

site_id	CC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE NO3 D 503

Chain	Residue
D	ARG104
D	PHE150
D	HIS275
D	ALA280
D	ILE282
D	LYS440

---

site_id	CC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO D 504

Chain	Residue
D	LYS372
D	LEU391
D	ARG392
D	HOH808
D	HOH874
D	HOH1081

---

site_id	CC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE EDO D 505

Chain	Residue
D	THR375
D	HOH829

---

site_id	CC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE EDO D 506

Chain	Residue
D	HOH908

---

site_id	CC6
Number of Residues	8
Details	BINDING SITE FOR RESIDUE EDO D 507

Chain	Residue
B	NO3504
D	ARG104
D	TRP271
D	LYS440
D	ARG441
D	VAL442
D	HOH917
D	HOH1027

---

site_id	CC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL D 508

Chain	Residue
B	HOH674
D	ASP263
D	ASN267
D	ARG300
D	HOH822
D	HOH1137

---

Functional Information from PROSITE/UniProt

site_id	PS00070
Number of Residues	12
Details	ALDEHYDE_DEHYDR_CYS Aldehyde dehydrogenases cysteine active site. FhNQGQACIAGS

Chain	Residue	Details
A	PHE274-SER285

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