4O5M

X-ray Crystal Structure of Isovaleryl-CoA Dehydrogenase from Brucella suis

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003995	molecular_function	acyl-CoA dehydrogenase activity
A	0006552	biological_process	L-leucine catabolic process
A	0008470	molecular_function	isovaleryl-CoA dehydrogenase activity
A	0016491	molecular_function	oxidoreductase activity
A	0016627	molecular_function	oxidoreductase activity, acting on the CH-CH group of donors
A	0016937	molecular_function	short-chain fatty acyl-CoA dehydrogenase activity
A	0046872	molecular_function	metal ion binding
A	0050660	molecular_function	flavin adenine dinucleotide binding
B	0003995	molecular_function	acyl-CoA dehydrogenase activity
B	0006552	biological_process	L-leucine catabolic process
B	0008470	molecular_function	isovaleryl-CoA dehydrogenase activity
B	0016491	molecular_function	oxidoreductase activity
B	0016627	molecular_function	oxidoreductase activity, acting on the CH-CH group of donors
B	0016937	molecular_function	short-chain fatty acyl-CoA dehydrogenase activity
B	0046872	molecular_function	metal ion binding
B	0050660	molecular_function	flavin adenine dinucleotide binding
C	0003995	molecular_function	acyl-CoA dehydrogenase activity
C	0006552	biological_process	L-leucine catabolic process
C	0008470	molecular_function	isovaleryl-CoA dehydrogenase activity
C	0016491	molecular_function	oxidoreductase activity
C	0016627	molecular_function	oxidoreductase activity, acting on the CH-CH group of donors
C	0016937	molecular_function	short-chain fatty acyl-CoA dehydrogenase activity
C	0046872	molecular_function	metal ion binding
C	0050660	molecular_function	flavin adenine dinucleotide binding
D	0003995	molecular_function	acyl-CoA dehydrogenase activity
D	0006552	biological_process	L-leucine catabolic process
D	0008470	molecular_function	isovaleryl-CoA dehydrogenase activity
D	0016491	molecular_function	oxidoreductase activity
D	0016627	molecular_function	oxidoreductase activity, acting on the CH-CH group of donors
D	0016937	molecular_function	short-chain fatty acyl-CoA dehydrogenase activity
D	0046872	molecular_function	metal ion binding
D	0050660	molecular_function	flavin adenine dinucleotide binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CA A 401

Chain	Residue
A	GLU57

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site_id	AC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE PG5 B 401

Chain	Residue
B	LEU5
B	ALA301
D	ALA301

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site_id	AC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE PG5 C 401

Chain	Residue
C	LEU5
C	ALA297
C	HOH522

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site_id	AC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE PG5 D 401

Chain	Residue
D	LYS269
D	GLN270

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Functional Information from PROSITE/UniProt

site_id	PS00072
Number of Residues	13
Details	ACYL_COA_DH_1 Acyl-CoA dehydrogenases signature 1. AMSEpgAGSDvvS

Chain	Residue	Details
A	ALA124-SER136

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site_id	PS00073
Number of Residues	20
Details	ACYL_COA_DH_2 Acyl-CoA dehydrogenases signature 2. QsLGGnGYinDyptgRllrD

Chain	Residue	Details
A	GLN336-ASP355

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