4O4Z
MURINE NEUROGLOBIN UNDER 30 BAR PRESSURE NITROUS Oxide
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0001666 | biological_process | response to hypoxia |
| A | 0005092 | molecular_function | GDP-dissociation inhibitor activity |
| A | 0005344 | molecular_function | oxygen carrier activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005739 | cellular_component | mitochondrion |
| A | 0005759 | cellular_component | mitochondrial matrix |
| A | 0005829 | cellular_component | cytosol |
| A | 0015671 | biological_process | oxygen transport |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0019825 | molecular_function | oxygen binding |
| A | 0020037 | molecular_function | heme binding |
| A | 0031175 | biological_process | neuron projection development |
| A | 0043066 | biological_process | negative regulation of apoptotic process |
| A | 0043204 | cellular_component | perikaryon |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0070301 | biological_process | cellular response to hydrogen peroxide |
| A | 0071456 | biological_process | cellular response to hypoxia |
| A | 0098809 | molecular_function | nitrite reductase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE HEM A 201 |
| Chain | Residue |
| A | LEU41 |
| A | LYS95 |
| A | HIS96 |
| A | VAL101 |
| A | N2O206 |
| A | HOH307 |
| A | HOH312 |
| A | HOH312 |
| A | HOH328 |
| A | PHE42 |
| A | TYR44 |
| A | HIS64 |
| A | LYS67 |
| A | LYS67 |
| A | VAL68 |
| A | TYR88 |
| A | LEU92 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 202 |
| Chain | Residue |
| A | SER19 |
| A | PRO20 |
| A | LEU21 |
| A | GLU22 |
| A | ARG66 |
| A | HOH353 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE N2O A 203 |
| Chain | Residue |
| A | LYS67 |
| A | TYR88 |
| A | SER91 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE N2O A 204 |
| Chain | Residue |
| A | PHE28 |
| A | ALA29 |
| A | PHE32 |
| A | PRO52 |
| A | SER55 |
| A | LEU56 |
| A | PHE61 |
| A | HOH323 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE N2O A 205 |
| Chain | Residue |
| A | LEU113 |
| A | TYR137 |
| A | VAL140 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE N2O A 206 |
| Chain | Residue |
| A | LEU27 |
| A | VAL109 |
| A | TYR137 |
| A | HEM201 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE N2O A 207 |
| Chain | Residue |
| A | SER17 |
| A | MET69 |
| A | ASP73 |
| A | HOH315 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | BINDING: distal binding residue; reversible => ECO:0000255|PROSITE-ProRule:PRU00238, ECO:0000269|PubMed:15162488, ECO:0007744|PDB:1Q1F |
| Chain | Residue | Details |
| A | HIS64 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | BINDING: proximal binding residue => ECO:0000255|PROSITE-ProRule:PRU00238, ECO:0000269|PubMed:15162488, ECO:0000269|PubMed:15548613, ECO:0007744|PDB:1Q1F, ECO:0007744|PDB:1W92 |
| Chain | Residue | Details |
| A | HIS96 |
