4O4E
Crystal Structure of an Inositol hexakisphosphate kinase EhIP6KA in complexed with ATP and Ins(1,3,4,5,6)P5
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005524 | molecular_function | ATP binding |
| A | 0016301 | molecular_function | kinase activity |
| A | 0032958 | biological_process | inositol phosphate biosynthetic process |
| A | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MG A 401 |
| Chain | Residue |
| A | GLY23 |
| A | MG402 |
| A | 5MY403 |
| A | ATP404 |
| A | HOH636 |
| A | HOH639 |
| A | HOH640 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MG A 402 |
| Chain | Residue |
| A | ATP404 |
| A | HOH623 |
| A | HOH636 |
| A | HOH639 |
| A | HOH667 |
| A | ASP231 |
| A | MG401 |
| site_id | AC3 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE 5MY A 403 |
| Chain | Residue |
| A | GLY23 |
| A | GLN27 |
| A | LYS101 |
| A | LYS115 |
| A | LYS118 |
| A | ARG119 |
| A | ARG152 |
| A | TYR153 |
| A | GLU242 |
| A | MG401 |
| A | ATP404 |
| A | HOH615 |
| A | HOH620 |
| A | HOH636 |
| A | HOH639 |
| A | HOH640 |
| A | HOH645 |
| A | HOH670 |
| A | HOH684 |
| A | HOH690 |
| site_id | AC4 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE ATP A 404 |
| Chain | Residue |
| A | GLY23 |
| A | SER24 |
| A | PHE25 |
| A | GLN27 |
| A | LEU36 |
| A | LYS38 |
| A | PHE77 |
| A | MET85 |
| A | GLU86 |
| A | ASN87 |
| A | LEU88 |
| A | ASP99 |
| A | ASP231 |
| A | ALA233 |
| A | MG401 |
| A | MG402 |
| A | 5MY403 |
| A | HOH611 |
| A | HOH619 |
| A | HOH633 |
| A | HOH636 |
| A | HOH638 |
| A | HOH639 |
| A | HOH694 |
| site_id | AC5 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE PO4 A 405 |
| Chain | Residue |
| A | HIS73 |
| A | HIS73 |
| A | HIS73 |
| A | HIS73 |
| A | HOH647 |
| A | HOH647 |
| A | HOH647 |
| A | HOH647 |
| A | HOH655 |
| A | HOH655 |
| A | HOH655 |
| A | HOH655 |
