Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0015276 | molecular_function | ligand-gated monoatomic ion channel activity |
| A | 0016020 | cellular_component | membrane |
| B | 0015276 | molecular_function | ligand-gated monoatomic ion channel activity |
| B | 0016020 | cellular_component | membrane |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 301 |
| Chain | Residue |
| A | ARG148 |
| A | ARG163 |
| A | HOH496 |
| B | HIS23 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 302 |
| Chain | Residue |
| A | HIS46 |
| A | ARG172 |
| A | GLU176 |
| A | LYS240 |
| A | GLN244 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 303 |
| Chain | Residue |
| A | SER217 |
| A | HOH639 |
| B | MET107 |
| B | SER108 |
| B | GOL304 |
| B | HOH565 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 304 |
| Chain | Residue |
| A | LYS116 |
| A | LYS185 |
| A | HOH429 |
| B | ILE70 |
| B | HOH604 |
| site_id | AC5 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE GOL A 305 |
| Chain | Residue |
| A | PRO105 |
| A | PHE106 |
| A | MET107 |
| A | SER108 |
| A | ASN242 |
| A | HOH459 |
| A | HOH499 |
| A | HOH614 |
| A | HOH636 |
| B | SER217 |
| B | LYS218 |
| B | GLY219 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 306 |
| Chain | Residue |
| A | VAL99 |
| A | LYS226 |
| A | HOH451 |
| B | GLY118 |
| B | THR119 |
| B | HOH503 |
| site_id | AC7 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL A 307 |
| site_id | AC8 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE PEG A 308 |
| Chain | Residue |
| A | SER108 |
| A | LEU109 |
| A | SER194 |
| A | THR195 |
| A | GLU198 |
| A | ASN214 |
| A | SER217 |
| A | HOH454 |
| A | HOH575 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ACT A 309 |
| Chain | Residue |
| A | TYR61 |
| A | ARG96 |
| A | SER142 |
| A | HOH470 |
| A | HOH649 |
| A | HOH650 |
| site_id | BC1 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE GLU B 301 |
| Chain | Residue |
| B | TYR61 |
| B | PRO89 |
| B | LEU90 |
| B | THR91 |
| B | ARG96 |
| B | GLY141 |
| B | SER142 |
| B | THR143 |
| B | GLU193 |
| B | HOH403 |
| B | HOH432 |
| B | HOH502 |
| site_id | BC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 B 302 |
| Chain | Residue |
| B | SER140 |
| B | LYS144 |
| B | ARG148 |
| B | HOH413 |
| B | HOH440 |
| B | HOH469 |
| B | HOH589 |
| site_id | BC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL B 303 |
| Chain | Residue |
| B | LYS116 |
| B | LYS185 |
| B | HOH438 |
| site_id | BC4 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE GOL B 304 |
| Chain | Residue |
| A | SER217 |
| A | LYS218 |
| A | SO4303 |
| A | HOH575 |
| B | PRO105 |
| B | SER108 |
| B | ASN242 |
| B | HOH588 |
| B | HOH663 |
| site_id | BC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL B 305 |
| Chain | Residue |
| A | ASN214 |
| A | ASP216 |
| A | SER217 |
| B | ASP248 |
| B | ASN252 |
| site_id | BC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PG4 B 306 |
| Chain | Residue |
| A | GLU24 |
| B | LYS144 |
| B | ARG148 |
| B | TRP159 |
| B | ARG163 |
| B | PHE170 |
| B | HOH608 |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | TYR61 | |
| A | ARG96 | |
| A | GLU193 | |
| B | TYR61 | |
| B | ARG96 | |
| B | GLU193 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | PRO89 | |
| B | PRO89 | |
| Chain | Residue | Details |
| A | THR91 | |
| A | SER142 | |
| A | THR143 | |
| B | THR91 | |
| B | SER142 | |
| B | THR143 | |
| site_id | SWS_FT_FI4 |
| Number of Residues | 6 |
| Details | SITE: Interaction with the cone snail toxin Con-ikot-ikot => ECO:0000269|PubMed:25103405 |
| Chain | Residue | Details |
| A | ARG64 | |
| A | ARG148 | |
| A | LYS240 | |
| B | ARG64 | |
| B | ARG148 | |
| B | LYS240 | |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | SITE: Crucial to convey clamshell closure to channel opening => ECO:0000269|PubMed:25103405 |
| Chain | Residue | Details |
| A | ILE121 | |
| B | ILE121 | |
| Chain | Residue | Details |
| A | SER150 | |
| B | SER150 | |
| Chain | Residue | Details |
| A | SER184 | |
| B | SER184 | |
| site_id | SWS_FT_FI8 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | ASN3 | |
| B | ASN3 | |
