4O2G

Crystal structure of carbomonoxy murine neuroglobin mutant V140W

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005092	molecular_function	GDP-dissociation inhibitor activity
A	0005344	molecular_function	oxygen carrier activity
A	0005515	molecular_function	protein binding
A	0005737	cellular_component	cytoplasm
A	0005739	cellular_component	mitochondrion
A	0005759	cellular_component	mitochondrial matrix
A	0005829	cellular_component	cytosol
A	0015671	biological_process	oxygen transport
A	0016491	molecular_function	oxidoreductase activity
A	0019825	molecular_function	oxygen binding
A	0020037	molecular_function	heme binding
A	0046872	molecular_function	metal ion binding
A	0071456	biological_process	cellular response to hypoxia
A	0098809	molecular_function	nitrite reductase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	16
Details	BINDING SITE FOR RESIDUE HEM A 201

Chain	Residue
A	LEU41
A	VAL101
A	SER105
A	PHE106
A	VAL109
A	TYR137
A	MET144
A	CMO202
A	PHE42
A	TYR44
A	HIS64
A	LYS67
A	LYS67
A	VAL71
A	LEU92
A	HIS96

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site_id	AC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CMO A 202

Chain	Residue
A	HIS64
A	HEM201

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	BINDING: distal binding residue; reversible => ECO:0000255|PROSITE-ProRule:PRU00238, ECO:0000269|PubMed:15162488, ECO:0007744|PDB:1Q1F

Chain	Residue	Details
A	HIS64

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site_id	SWS_FT_FI2
Number of Residues	1
Details	BINDING: proximal binding residue => ECO:0000255|PROSITE-ProRule:PRU00238, ECO:0000269|PubMed:15162488, ECO:0000269|PubMed:15548613, ECO:0007744|PDB:1Q1F, ECO:0007744|PDB:1W92

Chain	Residue	Details
A	HIS96

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