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4O1E

Structure of a methyltransferase component in complex with MTHF involved in O-demethylation

Functional Information from GO Data
ChainGOidnamespacecontents
A0005829cellular_componentcytosol
A0008168molecular_functionmethyltransferase activity
A0008705molecular_functionmethionine synthase activity
A0009086biological_processmethionine biosynthetic process
A0016740molecular_functiontransferase activity
A0032259biological_processmethylation
A0042558biological_processpteridine-containing compound metabolic process
A0071267biological_processL-methionine salvage
B0005829cellular_componentcytosol
B0008168molecular_functionmethyltransferase activity
B0008705molecular_functionmethionine synthase activity
B0009086biological_processmethionine biosynthetic process
B0016740molecular_functiontransferase activity
B0032259biological_processmethylation
B0042558biological_processpteridine-containing compound metabolic process
B0071267biological_processL-methionine salvage
Functional Information from PDB Data
site_idAC1
Number of Residues15
DetailsBINDING SITE FOR RESIDUE C2F A 3000
ChainResidue
AGLU7
AASN232
AHOH3101
AHOH3107
AHOH3122
AHOH3137
AHOH3280
ALYS8
AASP76
AASN97
AASP161
AGLY196
ALYS208
AILE227
AASP229

site_idAC2
Number of Residues15
DetailsBINDING SITE FOR RESIDUE C2F B 4000
ChainResidue
BGLU7
BLYS8
BASP76
BASN97
BASP161
BGLY196
BLYS208
BILE227
BASP229
BASN232
BHOH4110
BHOH4111
BHOH4115
BHOH4156
BHOH4221

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PDB entries from 2025-06-18

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