4NZH
A. fumigatus flavin-dependent ornithine monooxygenase R279A mutant
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004497 | molecular_function | monooxygenase activity |
| A | 0004499 | molecular_function | N,N-dimethylaniline monooxygenase activity |
| A | 0005506 | molecular_function | iron ion binding |
| A | 0006696 | biological_process | ergosterol biosynthetic process |
| A | 0006879 | biological_process | intracellular iron ion homeostasis |
| A | 0010106 | biological_process | cellular response to iron ion starvation |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0019290 | biological_process | siderophore biosynthetic process |
| A | 0031169 | biological_process | ferrichrome biosynthetic process |
| A | 0031172 | molecular_function | ornithine N5-monooxygenase activity |
| A | 0033214 | biological_process | siderophore-iron import into cell |
| A | 0044550 | biological_process | secondary metabolite biosynthetic process |
| A | 0070401 | molecular_function | NADP+ binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 30 |
| Details | BINDING SITE FOR RESIDUE FAD A 601 |
| Chain | Residue |
| A | GLY46 |
| A | HIS91 |
| A | MET94 |
| A | GLN102 |
| A | ILE103 |
| A | GLU166 |
| A | GLU167 |
| A | VAL168 |
| A | ALA209 |
| A | ILE210 |
| A | GLY211 |
| A | GLY48 |
| A | TYR407 |
| A | SER466 |
| A | LEU467 |
| A | LEU468 |
| A | HOH703 |
| A | HOH738 |
| A | HOH758 |
| A | HOH796 |
| A | HOH843 |
| A | HOH883 |
| A | PRO49 |
| A | HOH892 |
| A | ALA50 |
| A | LEU82 |
| A | GLU83 |
| A | ARG84 |
| A | GLN85 |
| A | TRP90 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE ORN A 602 |
| Chain | Residue |
| A | ILE103 |
| A | LYS107 |
| A | ASN293 |
| A | PHE296 |
| A | ASN323 |
| A | SER469 |
| A | HOH741 |
| A | HOH800 |
| A | HOH829 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 603 |
| Chain | Residue |
| A | LYS128 |
| A | ASP149 |
| A | ARG152 |
| A | TRP153 |
| A | GLN156 |
| A | PRO178 |
| A | HOH876 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 604 |
| Chain | Residue |
| A | LEU239 |
| A | LEU240 |
| A | LYS241 |
| A | LYS245 |
| A | TYR247 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 605 |
| Chain | Residue |
| A | PHE291 |
| A | GLU294 |
| A | MET339 |
| A | TYR340 |
| A | ARG343 |
| A | HOH878 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 606 |
| Chain | Residue |
| A | GLU366 |
| A | HIS367 |
| A | HIS368 |
| A | GLY369 |
| A | HOH880 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 24 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"22928747","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
