4NY7
Bond length analysis of the PqqC Y175F mutant structure shows evidence for bound PQQ in the reduced form
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0006725 | biological_process | obsolete cellular aromatic compound metabolic process |
| A | 0006790 | biological_process | sulfur compound metabolic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0018189 | biological_process | pyrroloquinoline quinone biosynthetic process |
| A | 0033732 | molecular_function | pyrroloquinoline-quinone synthase activity |
| A | 0044281 | biological_process | small molecule metabolic process |
| A | 1901360 | biological_process | organic cyclic compound metabolic process |
| B | 0006725 | biological_process | obsolete cellular aromatic compound metabolic process |
| B | 0006790 | biological_process | sulfur compound metabolic process |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0018189 | biological_process | pyrroloquinoline quinone biosynthetic process |
| B | 0033732 | molecular_function | pyrroloquinoline-quinone synthase activity |
| B | 0044281 | biological_process | small molecule metabolic process |
| B | 1901360 | biological_process | organic cyclic compound metabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE PQQ A 301 |
| Chain | Residue |
| A | TYR23 |
| A | THR146 |
| A | ILE153 |
| A | HIS154 |
| A | ARG157 |
| A | PHE175 |
| A | ARG179 |
| A | LYS214 |
| A | CL304 |
| A | HOH437 |
| A | HIS24 |
| A | ARG50 |
| A | TYR53 |
| A | GLN54 |
| A | LYS60 |
| A | HIS84 |
| A | TYR128 |
| A | SER144 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 302 |
| Chain | Residue |
| A | LYS76 |
| A | TRP77 |
| A | ARG80 |
| A | ARG185 |
| A | ASP186 |
| A | HIS189 |
| A | HOH531 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 303 |
| Chain | Residue |
| A | ARG233 |
| A | HOH661 |
| B | TYR29 |
| B | THR226 |
| B | HOH588 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 304 |
| Chain | Residue |
| A | ALA150 |
| A | HIS154 |
| A | ARG179 |
| A | PQQ301 |
| site_id | AC5 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE GOL A 305 |
| Chain | Residue |
| A | GLY20 |
| A | ARG40 |
| A | PHE149 |
| A | GLN152 |
| A | HOH414 |
| A | HOH417 |
| A | HOH466 |
| A | HOH501 |
| A | HOH671 |
| site_id | AC6 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE GOL A 306 |
| Chain | Residue |
| A | ARG134 |
| A | ALA135 |
| A | CYS136 |
| A | VAL251 |
| A | HOH452 |
| A | HOH482 |
| A | HOH519 |
| A | HOH547 |
| A | HOH568 |
| A | HOH675 |
| A | HOH677 |
| B | HOH439 |
| B | HOH574 |
| B | HOH682 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL A 307 |
| Chain | Residue |
| A | THR6 |
| A | SER8 |
| A | PRO9 |
| site_id | AC8 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE PQQ B 301 |
| Chain | Residue |
| B | TYR23 |
| B | HIS24 |
| B | ARG50 |
| B | TYR53 |
| B | GLN54 |
| B | ILE57 |
| B | LYS60 |
| B | HIS84 |
| B | TYR128 |
| B | SER144 |
| B | THR146 |
| B | ILE153 |
| B | HIS154 |
| B | ARG157 |
| B | PHE175 |
| B | ARG179 |
| B | LYS214 |
| B | CL304 |
| B | HOH412 |
| site_id | AC9 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE GOL B 302 |
| Chain | Residue |
| B | LYS76 |
| B | TRP77 |
| B | GLN79 |
| B | ARG80 |
| B | ARG185 |
| B | ASP186 |
| B | HIS189 |
| B | HOH621 |
| B | HOH688 |
| site_id | BC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL B 303 |
| Chain | Residue |
| A | PRO28 |
| A | TYR29 |
| A | THR226 |
| A | ALA230 |
| A | LEU231 |
| A | HOH606 |
| B | ARG233 |
| B | HOH541 |
| site_id | BC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL B 304 |
| Chain | Residue |
| B | ALA183 |
| B | PQQ301 |
| B | ALA150 |
| B | HIS154 |
| B | ARG179 |
| site_id | BC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL B 305 |
| Chain | Residue |
| A | ASN130 |
| A | ARG133 |
| A | ARG133 |
| A | ARG134 |
| B | ARG133 |
| B | ARG133 |
| B | ARG134 |
| B | ARG134 |
| site_id | BC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL B 306 |
| Chain | Residue |
| B | GLN138 |
| B | GLU253 |
| B | HIS254 |
| B | HIS255 |
| B | HOH497 |
| B | HOH542 |
| site_id | BC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL B 307 |
| Chain | Residue |
| B | TYR229 |
| B | PRO234 |
| B | ASP241 |
| B | LYS242 |
| B | ALA243 |
| B | TRP245 |
| B | HOH537 |
| B | HOH655 |
