4NY3
Human PTPA in complex with peptide
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 401 |
| Chain | Residue |
| A | ARG86 |
| A | TRP87 |
| A | LYS111 |
| A | HOH589 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 A 402 |
| Chain | Residue |
| A | HOH742 |
| A | HOH761 |
| B | HOH790 |
| A | ASP229 |
| A | HIS230 |
| A | SER283 |
| A | TRP284 |
| A | SER285 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 403 |
| Chain | Residue |
| A | ARG41 |
| A | ARG200 |
| A | HOH570 |
| A | HOH872 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 A 404 |
| Chain | Residue |
| A | SER71 |
| A | GLU72 |
| A | LYS302 |
| A | HOH537 |
| A | HOH734 |
| A | HOH819 |
| A | HOH824 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 405 |
| Chain | Residue |
| A | ARG173 |
| A | VAL174 |
| A | HOH752 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE GOL A 406 |
| Chain | Residue |
| A | GLN289 |
| A | ARG293 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 401 |
| Chain | Residue |
| B | ARG86 |
| B | TRP87 |
| B | LYS111 |
| B | HOH665 |
| site_id | AC8 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO4 B 402 |
| Chain | Residue |
| B | ASP229 |
| B | SER283 |
| B | TRP284 |
| B | SER285 |
| B | HOH562 |
| B | HOH671 |
| B | HOH761 |
| B | HOH768 |
| B | HOH786 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B 403 |
| Chain | Residue |
| A | LYS310 |
| B | LYS310 |
| B | HOH574 |
| B | HOH647 |
| B | HOH801 |
| site_id | BC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 B 404 |
| Chain | Residue |
| B | ARG41 |
| B | ARG200 |
| B | HOH795 |
| site_id | BC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 B 405 |
| Chain | Residue |
| B | ARG173 |
| B | VAL174 |
| site_id | BC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE GOL B 406 |
| Chain | Residue |
| B | GLN289 |
| B | ARG293 |
| site_id | BC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL B 407 |
| Chain | Residue |
| B | PHE238 |
| B | VAL239 |
| B | ASP240 |
| B | GLU241 |
| B | VAL244 |
| B | ILE257 |
| B | THR261 |
| site_id | BC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL B 408 |
| Chain | Residue |
| B | SER71 |
| B | GLU72 |
| B | PRO304 |
| B | HOH822 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"16916641","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2HV7","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"16916641","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2HV6","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"P67774","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Leucine methyl ester","evidences":[{"source":"PubMed","id":"38123684","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"8206937","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8SO0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8TTB","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
