Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004590 | molecular_function | orotidine-5'-phosphate decarboxylase activity |
| A | 0005829 | cellular_component | cytosol |
| A | 0006207 | biological_process | 'de novo' pyrimidine nucleobase biosynthetic process |
| A | 0006221 | biological_process | pyrimidine nucleotide biosynthetic process |
| A | 0016831 | molecular_function | carboxy-lyase activity |
| A | 0044205 | biological_process | 'de novo' UMP biosynthetic process |
| B | 0004590 | molecular_function | orotidine-5'-phosphate decarboxylase activity |
| B | 0005829 | cellular_component | cytosol |
| B | 0006207 | biological_process | 'de novo' pyrimidine nucleobase biosynthetic process |
| B | 0006221 | biological_process | pyrimidine nucleotide biosynthetic process |
| B | 0016831 | molecular_function | carboxy-lyase activity |
| B | 0044205 | biological_process | 'de novo' UMP biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE UP6 A 301 |
| Chain | Residue |
| A | ASP20 |
| A | ARG203 |
| A | HOH405 |
| A | HOH410 |
| A | HOH413 |
| A | HOH416 |
| A | HOH419 |
| A | HOH420 |
| B | ASP75 |
| B | ILE76 |
| B | THR79 |
| A | LYS42 |
| A | ASP70 |
| A | LYS72 |
| A | MET126 |
| A | SER127 |
| A | PRO180 |
| A | GLN185 |
| A | GLY202 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL A 302 |
| Chain | Residue |
| A | ASP104 |
| A | ARG107 |
| B | GLY130 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 303 |
| Chain | Residue |
| A | PRO77 |
| A | GLU78 |
| B | HOH482 |
| B | HOH571 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 304 |
| Chain | Residue |
| A | ASP140 |
| A | ARG144 |
| A | ARG166 |
| A | ILE170 |
| A | HOH558 |
| A | HOH591 |
| site_id | AC5 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE UP6 B 301 |
| Chain | Residue |
| A | ASP75 |
| A | ILE76 |
| A | THR79 |
| B | ASP20 |
| B | LYS42 |
| B | ASP70 |
| B | LYS72 |
| B | MET126 |
| B | SER127 |
| B | PRO180 |
| B | GLN185 |
| B | GLY202 |
| B | ARG203 |
| B | HOH407 |
| B | HOH410 |
| B | HOH411 |
| B | HOH413 |
| B | HOH419 |
| B | HOH426 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL B 302 |
| Chain | Residue |
| A | GLY130 |
| B | ASP104 |
| B | GOL305 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL B 303 |
| Chain | Residue |
| A | HOH486 |
| B | PRO77 |
| B | GLU78 |
| site_id | AC8 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL B 304 |
| Chain | Residue |
| A | GLU33 |
| A | ASN210 |
| A | ALA212 |
| A | HOH427 |
| A | HOH430 |
| A | HOH483 |
| B | THR159 |
| B | PRO161 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL B 305 |
| Chain | Residue |
| B | ASP104 |
| B | ARG107 |
| B | LEU149 |
| B | CL302 |
| site_id | BC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG B 306 |
| Chain | Residue |
| B | HOH523 |
| B | HOH596 |
| B | HOH623 |
| B | HOH624 |
| B | HOH625 |
| site_id | BC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG B 307 |
| Chain | Residue |
| B | SER221 |
| B | HOH467 |
| B | HOH477 |
| B | HOH518 |
| B | HOH626 |
| B | HOH627 |
Functional Information from PROSITE/UniProt
| site_id | PS00156 |
| Number of Residues | 14 |
| Details | OMPDECASE Orotidine 5'-phosphate decarboxylase active site. IIaDfKvaDIPeTN |
| Chain | Residue | Details |
| A | ILE67-ASN80 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: Proton donor |
| Chain | Residue | Details |
| A | LYS72 | |
| B | LYS72 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 14 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | ASP20 | |
| B | ASP70 | |
| B | SER127 | |
| B | PRO180 | |
| B | GLY202 | |
| B | ARG203 | |
| A | LYS42 | |
| A | ASP70 | |
| A | SER127 | |
| A | PRO180 | |
| A | GLY202 | |
| A | ARG203 | |
| B | ASP20 | |
| B | LYS42 | |
