4NTM
QueD soaked with sepiapterin (selenomethionine substituted protein)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0008616 | biological_process | tRNA queuosine(34) biosynthetic process |
| A | 0016829 | molecular_function | lyase activity |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0070497 | molecular_function | 6-carboxytetrahydropterin synthase activity |
| B | 0008270 | molecular_function | zinc ion binding |
| B | 0008616 | biological_process | tRNA queuosine(34) biosynthetic process |
| B | 0016829 | molecular_function | lyase activity |
| B | 0042802 | molecular_function | identical protein binding |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0070497 | molecular_function | 6-carboxytetrahydropterin synthase activity |
| C | 0008270 | molecular_function | zinc ion binding |
| C | 0008616 | biological_process | tRNA queuosine(34) biosynthetic process |
| C | 0016829 | molecular_function | lyase activity |
| C | 0042802 | molecular_function | identical protein binding |
| C | 0046872 | molecular_function | metal ion binding |
| C | 0070497 | molecular_function | 6-carboxytetrahydropterin synthase activity |
| D | 0008270 | molecular_function | zinc ion binding |
| D | 0008616 | biological_process | tRNA queuosine(34) biosynthetic process |
| D | 0016829 | molecular_function | lyase activity |
| D | 0042802 | molecular_function | identical protein binding |
| D | 0046872 | molecular_function | metal ion binding |
| D | 0070497 | molecular_function | 6-carboxytetrahydropterin synthase activity |
| E | 0008270 | molecular_function | zinc ion binding |
| E | 0008616 | biological_process | tRNA queuosine(34) biosynthetic process |
| E | 0016829 | molecular_function | lyase activity |
| E | 0042802 | molecular_function | identical protein binding |
| E | 0046872 | molecular_function | metal ion binding |
| E | 0070497 | molecular_function | 6-carboxytetrahydropterin synthase activity |
| F | 0008270 | molecular_function | zinc ion binding |
| F | 0008616 | biological_process | tRNA queuosine(34) biosynthetic process |
| F | 0016829 | molecular_function | lyase activity |
| F | 0042802 | molecular_function | identical protein binding |
| F | 0046872 | molecular_function | metal ion binding |
| F | 0070497 | molecular_function | 6-carboxytetrahydropterin synthase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 201 |
| Chain | Residue |
| A | HIS16 |
| A | HIS31 |
| A | HIS33 |
| A | 2K8202 |
| site_id | AC2 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE 2K8 A 202 |
| Chain | Residue |
| A | GLU86 |
| A | GLU110 |
| A | ZN201 |
| C | HIS71 |
| E | TRP51 |
| E | ILE53 |
| E | ASP54 |
| E | PHE55 |
| A | HIS16 |
| A | HIS31 |
| A | HIS33 |
| A | THR84 |
| A | SER85 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN B 201 |
| Chain | Residue |
| B | HIS16 |
| B | HIS31 |
| B | HIS33 |
| B | GLU110 |
| B | 2K8202 |
| site_id | AC4 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE 2K8 B 202 |
| Chain | Residue |
| A | LEU6 |
| A | TRP51 |
| A | ILE53 |
| A | ASP54 |
| A | PHE55 |
| B | HIS16 |
| B | CYS27 |
| B | HIS31 |
| B | HIS33 |
| B | THR84 |
| B | SER85 |
| B | GLU86 |
| B | GLU110 |
| B | ZN201 |
| B | HOH332 |
| D | HIS71 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN C 201 |
| Chain | Residue |
| C | HIS16 |
| C | HIS31 |
| C | HIS33 |
| C | 2K8202 |
| site_id | AC6 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE 2K8 C 202 |
| Chain | Residue |
| A | HIS71 |
| C | HIS16 |
| C | LEU18 |
| C | CYS27 |
| C | HIS31 |
| C | HIS33 |
| C | THR84 |
| C | SER85 |
| C | GLU86 |
| C | GLU110 |
| C | ZN201 |
| D | LEU6 |
| D | TRP51 |
| D | ILE53 |
| D | ASP54 |
| D | PHE55 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN D 201 |
| Chain | Residue |
| D | HIS16 |
| D | HIS31 |
| D | HIS33 |
| D | GLU110 |
| D | 2K8202 |
| site_id | AC8 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE 2K8 D 202 |
| Chain | Residue |
| B | HIS71 |
| D | HIS16 |
| D | CYS27 |
| D | HIS31 |
| D | THR84 |
| D | SER85 |
| D | GLU86 |
| D | GLU110 |
| D | ZN201 |
| F | LEU6 |
| F | TRP51 |
| F | ILE53 |
| F | ASP54 |
| F | PHE55 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN E 201 |
| Chain | Residue |
| E | HIS16 |
| E | HIS31 |
| E | HIS33 |
| E | GLU110 |
| E | 2K8202 |
| site_id | BC1 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE 2K8 E 202 |
| Chain | Residue |
| B | LEU6 |
| B | TRP51 |
| B | ILE53 |
| B | ASP54 |
| B | PHE55 |
| E | HIS16 |
| E | CYS27 |
| E | HIS31 |
| E | HIS33 |
| E | THR84 |
| E | SER85 |
| E | GLU86 |
| E | GLU110 |
| E | ZN201 |
| F | HIS71 |
| site_id | BC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN F 201 |
| Chain | Residue |
| F | HIS33 |
| F | GLU110 |
| F | 2K8202 |
| F | HIS16 |
| F | HIS31 |
| site_id | BC3 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE 2K8 F 202 |
| Chain | Residue |
| C | LEU6 |
| C | TRP51 |
| C | ILE53 |
| C | ASP54 |
| C | PHE55 |
| E | HIS71 |
| F | HIS16 |
| F | CYS27 |
| F | HIS31 |
| F | HIS33 |
| F | THR84 |
| F | SER85 |
| F | GLU86 |
| F | GLU110 |
| F | ZN201 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | Active site: {"description":"Charge relay system","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 17 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
