4NTC
Crystal structure of GliT
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004791 | molecular_function | thioredoxin-disulfide reductase (NADPH) activity |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0036146 | biological_process | cellular response to mycotoxin |
| A | 0043386 | biological_process | mycotoxin biosynthetic process |
| A | 0045454 | biological_process | cell redox homeostasis |
| A | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| A | 0097237 | biological_process | cellular response to toxic substance |
| A | 0098869 | biological_process | cellular oxidant detoxification |
| A | 2001310 | biological_process | gliotoxin biosynthetic process |
| B | 0004791 | molecular_function | thioredoxin-disulfide reductase (NADPH) activity |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0036146 | biological_process | cellular response to mycotoxin |
| B | 0043386 | biological_process | mycotoxin biosynthetic process |
| B | 0045454 | biological_process | cell redox homeostasis |
| B | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| B | 0097237 | biological_process | cellular response to toxic substance |
| B | 0098869 | biological_process | cellular oxidant detoxification |
| B | 2001310 | biological_process | gliotoxin biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 38 |
| Details | BINDING SITE FOR RESIDUE FAD A 401 |
| Chain | Residue |
| A | GLY20 |
| A | TYR47 |
| A | ARG48 |
| A | ASN49 |
| A | THR52 |
| A | MET55 |
| A | HIS56 |
| A | VAL58 |
| A | SER89 |
| A | THR90 |
| A | ILE91 |
| A | ALA21 |
| A | ALA121 |
| A | THR122 |
| A | GLY123 |
| A | ASP126 |
| A | HIS144 |
| A | CYS148 |
| A | PHE261 |
| A | GLY293 |
| A | ASP294 |
| A | LYS300 |
| A | GLY22 |
| A | ALA301 |
| A | VAL302 |
| A | HOH502 |
| A | HOH506 |
| A | HOH510 |
| A | HOH511 |
| A | HOH523 |
| A | HOH540 |
| A | HOH585 |
| A | PRO23 |
| A | ALA24 |
| A | ASP43 |
| A | SER44 |
| A | GLY45 |
| A | VAL46 |
| site_id | AC2 |
| Number of Residues | 39 |
| Details | BINDING SITE FOR RESIDUE FAD B 401 |
| Chain | Residue |
| B | GLY20 |
| B | ALA21 |
| B | GLY22 |
| B | PRO23 |
| B | ALA24 |
| B | ASP43 |
| B | SER44 |
| B | GLY45 |
| B | VAL46 |
| B | TYR47 |
| B | ARG48 |
| B | ASN49 |
| B | THR52 |
| B | MET55 |
| B | HIS56 |
| B | VAL58 |
| B | SER89 |
| B | THR90 |
| B | ILE91 |
| B | ALA121 |
| B | THR122 |
| B | GLY123 |
| B | ASP126 |
| B | HIS144 |
| B | CYS148 |
| B | PHE261 |
| B | GLY293 |
| B | ASP294 |
| B | LYS300 |
| B | ALA301 |
| B | VAL302 |
| B | HOH501 |
| B | HOH505 |
| B | HOH506 |
| B | HOH525 |
| B | HOH531 |
| B | HOH548 |
| B | HOH570 |
| B | HOH625 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 26 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"24446392","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
