4NPT
Crystal Structure of HIV-1 Protease Multiple Mutant P51 Complexed with Darunavir
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| A | 0008233 | molecular_function | peptidase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0055036 | cellular_component | virion membrane |
| A | 0072494 | cellular_component | host multivesicular body |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE 017 A 401 |
| Chain | Residue |
| A | ASN25 |
| A | ILE72 |
| A | VAL84 |
| A | HOH514 |
| A | HOH525 |
| A | HOH525 |
| A | GLY27 |
| A | ILE47 |
| A | GLY48 |
| A | GLY49 |
| A | ILE50 |
| A | GLY52 |
| A | MET54 |
| A | GLN61 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL A 402 |
| Chain | Residue |
| A | GLY16 |
| A | GLY17 |
| A | PRO63 |
| A | ILE64 |
| A | HOH521 |
| A | HOH524 |
| A | HOH543 |
| A | HOH543 |
