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4NLV

Poliovirus Polymerase - G289A/C290F Loop Mutant

Functional Information from GO Data
ChainGOidnamespacecontents
A0003723molecular_functionRNA binding
A0003968molecular_functionRNA-dependent RNA polymerase activity
A0006351biological_processDNA-templated transcription
A0039694biological_processviral RNA genome replication
Functional Information from PDB Data
site_idAC1
Number of Residues5
DetailsBINDING SITE FOR RESIDUE ACY A 901
ChainResidue
AILE401
ATRP403
ATHR404
ATHR410
AHIS413

site_idAC2
Number of Residues1
DetailsBINDING SITE FOR RESIDUE ACY A 902
ChainResidue
AMET189

site_idAC3
Number of Residues4
DetailsBINDING SITE FOR RESIDUE ACY A 903
ChainResidue
AHOH1130
AMET392
AGLU396
ASER400

site_idAC4
Number of Residues5
DetailsBINDING SITE FOR RESIDUE ACY A 904
ChainResidue
ATYR334
AHIS336
APRO440
AARG443
AHOH1088

site_idAC5
Number of Residues1
DetailsBINDING SITE FOR RESIDUE ACY A 905
ChainResidue
AARG379

site_idAC6
Number of Residues3
DetailsBINDING SITE FOR RESIDUE 1PE A 909
ChainResidue
ASER219
APHE461
AHOH1108

site_idAC7
Number of Residues1
DetailsBINDING SITE FOR RESIDUE 1PE A 910
ChainResidue
APHE378

site_idAC8
Number of Residues6
DetailsBINDING SITE FOR RESIDUE NA A 911
ChainResidue
ALEU268
AASN269
ASER271
AGLY284
AGLY285
AHOH1104

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsBINDING: BINDING => ECO:0000269|PubMed:21148772
ChainResidueDetails
AASP233

site_idSWS_FT_FI2
Number of Residues1
DetailsBINDING: BINDING => ECO:0000269|PubMed:21148772, ECO:0000305|PubMed:2196557
ChainResidueDetails
AASP328

227111

PDB entries from 2024-11-06

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