4NJO
crystal structure of cofactor(NAD+) bound 3-phosphoglycerate dehydrogenase in Entamoeba histolytica
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004617 | molecular_function | phosphoglycerate dehydrogenase activity |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0051287 | molecular_function | NAD binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0004617 | molecular_function | phosphoglycerate dehydrogenase activity |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| B | 0042802 | molecular_function | identical protein binding |
| B | 0051287 | molecular_function | NAD binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR RESIDUE NAD A 401 |
| Chain | Residue |
| A | ALA78 |
| A | PHE164 |
| A | HIS187 |
| A | LEU188 |
| A | PRO189 |
| A | GLU193 |
| A | THR194 |
| A | THR215 |
| A | ALA216 |
| A | ARG217 |
| A | ASP241 |
| A | ASN102 |
| A | LYS263 |
| A | GLY265 |
| A | ALA266 |
| A | FMT402 |
| A | HOH507 |
| A | HOH519 |
| A | VAL106 |
| A | GLY139 |
| A | GLY141 |
| A | TYR142 |
| A | VAL143 |
| A | ASP162 |
| A | PRO163 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE FMT A 402 |
| Chain | Residue |
| A | ARG75 |
| A | ALA78 |
| A | GLY79 |
| A | ARG217 |
| A | LYS263 |
| A | NAD401 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE FMT B 401 |
| Chain | Residue |
| B | ARG75 |
| B | GLY77 |
| B | ALA78 |
| B | GLY79 |
| B | ASN102 |
| B | ARG217 |
| B | GOL403 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE TRS B 402 |
| Chain | Residue |
| B | GLY141 |
| B | TYR142 |
| B | VAL143 |
| B | GLY144 |
| B | HIS187 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL B 403 |
| Chain | Residue |
| B | LYS9 |
| B | ARG55 |
| B | SER56 |
| B | ARG75 |
| B | ALA266 |
| B | FMT401 |
