4NG3
Crystal structure of 5-carboxyvanillate decarboxylase from Sphingomonas paucimobilis complexed with 4-Hydroxy-3-methoxy-5-nitrobenzoic acid
Replaces: 4L5PFunctional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0016829 | molecular_function | lyase activity |
| A | 0016831 | molecular_function | carboxy-lyase activity |
| A | 0019748 | biological_process | secondary metabolic process |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0016829 | molecular_function | lyase activity |
| B | 0016831 | molecular_function | carboxy-lyase activity |
| B | 0019748 | biological_process | secondary metabolic process |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0005829 | cellular_component | cytosol |
| C | 0016787 | molecular_function | hydrolase activity |
| C | 0016829 | molecular_function | lyase activity |
| C | 0016831 | molecular_function | carboxy-lyase activity |
| C | 0019748 | biological_process | secondary metabolic process |
| C | 0046872 | molecular_function | metal ion binding |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0005829 | cellular_component | cytosol |
| D | 0016787 | molecular_function | hydrolase activity |
| D | 0016829 | molecular_function | lyase activity |
| D | 0016831 | molecular_function | carboxy-lyase activity |
| D | 0019748 | biological_process | secondary metabolic process |
| D | 0046872 | molecular_function | metal ion binding |
| E | 0005737 | cellular_component | cytoplasm |
| E | 0005829 | cellular_component | cytosol |
| E | 0016787 | molecular_function | hydrolase activity |
| E | 0016829 | molecular_function | lyase activity |
| E | 0016831 | molecular_function | carboxy-lyase activity |
| E | 0019748 | biological_process | secondary metabolic process |
| E | 0046872 | molecular_function | metal ion binding |
| F | 0005737 | cellular_component | cytoplasm |
| F | 0005829 | cellular_component | cytosol |
| F | 0016787 | molecular_function | hydrolase activity |
| F | 0016829 | molecular_function | lyase activity |
| F | 0016831 | molecular_function | carboxy-lyase activity |
| F | 0019748 | biological_process | secondary metabolic process |
| F | 0046872 | molecular_function | metal ion binding |
| G | 0005737 | cellular_component | cytoplasm |
| G | 0005829 | cellular_component | cytosol |
| G | 0016787 | molecular_function | hydrolase activity |
| G | 0016829 | molecular_function | lyase activity |
| G | 0016831 | molecular_function | carboxy-lyase activity |
| G | 0019748 | biological_process | secondary metabolic process |
| G | 0046872 | molecular_function | metal ion binding |
| H | 0005737 | cellular_component | cytoplasm |
| H | 0005829 | cellular_component | cytosol |
| H | 0016787 | molecular_function | hydrolase activity |
| H | 0016829 | molecular_function | lyase activity |
| H | 0016831 | molecular_function | carboxy-lyase activity |
| H | 0019748 | biological_process | secondary metabolic process |
| H | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MN A 401 |
| Chain | Residue |
| A | GLU7 |
| A | HIS173 |
| A | ASP296 |
| A | 1DF402 |
| A | HOH726 |
| site_id | AC2 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE 1DF A 402 |
| Chain | Residue |
| A | ALA77 |
| A | HIS173 |
| A | SER192 |
| A | HIS226 |
| A | ASP296 |
| A | TYR299 |
| A | MN401 |
| A | HOH512 |
| A | HOH520 |
| A | HOH533 |
| A | HOH585 |
| A | HOH650 |
| H | ARG237 |
| H | ASN244 |
| A | GLU7 |
| A | LEU34 |
| A | ARG45 |
| A | THR76 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 403 |
| Chain | Residue |
| A | TYR240 |
| A | MET241 |
| A | GLY243 |
| A | ASN244 |
| A | HOH615 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MN B 401 |
| Chain | Residue |
| B | GLU7 |
| B | HIS173 |
| B | ASP296 |
| B | 1DF402 |
| B | HOH740 |
| site_id | AC5 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE 1DF B 402 |
| Chain | Residue |
| B | GLU7 |
| B | LEU34 |
| B | ARG45 |
| B | THR76 |
| B | ALA77 |
| B | HIS173 |
| B | SER192 |
| B | HIS226 |
| B | ASP296 |
| B | TYR299 |
| B | MN401 |
| B | HOH516 |
| B | HOH532 |
| B | HOH558 |
| B | HOH564 |
| B | HOH566 |
| G | ARG237 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PEG B 403 |
| Chain | Residue |
| B | TYR240 |
| B | MET241 |
| B | GLY243 |
| B | ASN244 |
| B | HOH609 |
| B | HOH855 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MN C 401 |
| Chain | Residue |
| C | GLU7 |
| C | HIS173 |
| C | ASP296 |
| C | 1DF402 |
| C | HOH834 |
| site_id | AC8 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE 1DF C 402 |
| Chain | Residue |
| C | GLU7 |
| C | LEU34 |
| C | ARG45 |
| C | THR76 |
| C | ALA77 |
| C | HIS173 |
| C | SER192 |
| C | ALA193 |
| C | HIS226 |
| C | ASP296 |
| C | TYR299 |
| C | MN401 |
| C | HOH515 |
| C | HOH531 |
| C | HOH533 |
| C | HOH538 |
| C | HOH834 |
| C | HOH843 |
| F | ARG237 |
| F | ASN244 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO C 403 |
| Chain | Residue |
| C | TYR240 |
| C | MET241 |
| C | GLY243 |
| C | ASN244 |
| C | HOH593 |
| site_id | BC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MN D 401 |
| Chain | Residue |
| D | GLU7 |
| D | HIS173 |
| D | ASP296 |
| D | 1DF402 |
| D | HOH759 |
| site_id | BC2 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE 1DF D 402 |
| Chain | Residue |
| D | HIS226 |
| D | ASP296 |
| D | TYR299 |
| D | MN401 |
| D | HOH521 |
| D | HOH545 |
| D | HOH557 |
| D | HOH559 |
| D | HOH625 |
| E | ARG237 |
| E | ASN244 |
| D | GLU7 |
| D | LEU34 |
| D | ARG45 |
| D | THR76 |
| D | ALA77 |
| D | HIS173 |
| D | SER192 |
| D | ALA193 |
| site_id | BC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO D 403 |
| Chain | Residue |
| D | TYR240 |
| D | MET241 |
| D | GLY243 |
| D | ASN244 |
| D | HOH587 |
| site_id | BC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MN E 401 |
| Chain | Residue |
| E | GLU7 |
| E | HIS173 |
| E | ASP296 |
| E | 1DF402 |
| E | HOH837 |
| site_id | BC5 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE 1DF E 402 |
| Chain | Residue |
| D | ARG237 |
| D | ASN244 |
| E | GLU7 |
| E | LEU34 |
| E | ARG45 |
| E | THR76 |
| E | ALA77 |
| E | HIS173 |
| E | SER192 |
| E | HIS226 |
| E | ASP296 |
| E | TYR299 |
| E | MN401 |
| E | HOH504 |
| E | HOH510 |
| E | HOH513 |
| E | HOH589 |
| E | HOH684 |
| site_id | BC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PEG E 403 |
| Chain | Residue |
| E | TYR240 |
| E | MET241 |
| E | GLY243 |
| E | ASN244 |
| E | HOH682 |
| site_id | BC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PEG E 404 |
| Chain | Residue |
| E | ARG45 |
| E | PRO46 |
| E | ALA47 |
| E | MET48 |
| E | ARG51 |
| G | ASP41 |
| site_id | BC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO E 405 |
| Chain | Residue |
| E | ASP152 |
| E | HIS157 |
| E | SER211 |
| E | LEU213 |
| E | ARG216 |
| E | HOH678 |
| E | HOH741 |
| site_id | BC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO E 406 |
| Chain | Residue |
| E | PHE308 |
| E | THR311 |
| E | HOH543 |
| E | HOH780 |
| F | ARG263 |
| site_id | CC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MN F 401 |
| Chain | Residue |
| F | GLU7 |
| F | HIS173 |
| F | ASP296 |
| F | 1DF402 |
| F | HOH830 |
| site_id | CC2 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE 1DF F 402 |
| Chain | Residue |
| C | ARG237 |
| C | ASN244 |
| F | GLU7 |
| F | LEU34 |
| F | ARG45 |
| F | THR76 |
| F | ALA77 |
| F | HIS173 |
| F | SER192 |
| F | HIS226 |
| F | ASP296 |
| F | TYR299 |
| F | MN401 |
| F | HOH502 |
| F | HOH513 |
| F | HOH527 |
| F | HOH568 |
| F | HOH632 |
| F | HOH830 |
| site_id | CC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PEG F 403 |
| Chain | Residue |
| F | TYR240 |
| F | MET241 |
| F | GLY243 |
| F | ASN244 |
| F | HOH631 |
| site_id | CC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MN G 401 |
| Chain | Residue |
| G | GLU7 |
| G | HIS173 |
| G | ASP296 |
| G | 1DF402 |
| G | HOH834 |
| site_id | CC5 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE 1DF G 402 |
| Chain | Residue |
| B | ARG237 |
| G | GLU7 |
| G | LEU34 |
| G | ARG45 |
| G | THR76 |
| G | ALA77 |
| G | HIS173 |
| G | SER192 |
| G | HIS226 |
| G | ASP296 |
| G | TYR299 |
| G | MN401 |
| G | HOH509 |
| G | HOH510 |
| G | HOH531 |
| G | HOH533 |
| G | HOH600 |
| G | HOH834 |
| site_id | CC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO G 403 |
| Chain | Residue |
| G | TYR240 |
| G | MET241 |
| G | GLY243 |
| G | ASN244 |
| G | HOH586 |
| site_id | CC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MN H 401 |
| Chain | Residue |
| H | GLU7 |
| H | HIS173 |
| H | ASP296 |
| H | 1DF402 |
| H | HOH821 |
| site_id | CC8 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE 1DF H 402 |
| Chain | Residue |
| A | ARG237 |
| A | ASN244 |
| H | GLU7 |
| H | LEU34 |
| H | ARG45 |
| H | THR76 |
| H | ALA77 |
| H | HIS173 |
| H | SER192 |
| H | ALA193 |
| H | HIS226 |
| H | ASP296 |
| H | TYR299 |
| H | MN401 |
| H | HOH509 |
| H | HOH524 |
| H | HOH528 |
| H | HOH556 |
| H | HOH676 |
| H | HOH821 |
| site_id | CC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PEG H 403 |
| Chain | Residue |
| H | TYR240 |
| H | MET241 |
| H | GLY243 |
| H | ASN244 |
| H | HOH613 |
| site_id | DC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO H 404 |
| Chain | Residue |
| H | HIS242 |
| H | LEU254 |
| H | LYS255 |
| H | LEU256 |
| H | HOH571 |
| H | HOH578 |
| site_id | DC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO H 405 |
| Chain | Residue |
| H | HIS276 |
| H | PHE308 |
| H | THR311 |
| H | HOH616 |
| H | HOH683 |
