4NFT

Crystal structure of human lnkH2B-h2A.Z-Anp32e

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000786	cellular_component	nucleosome
A	0003677	molecular_function	DNA binding
A	0030527	molecular_function	structural constituent of chromatin
A	0046982	molecular_function	protein heterodimerization activity
B	0000786	cellular_component	nucleosome
B	0003677	molecular_function	DNA binding
B	0030527	molecular_function	structural constituent of chromatin
B	0046982	molecular_function	protein heterodimerization activity
C	0000786	cellular_component	nucleosome
C	0003677	molecular_function	DNA binding
C	0030527	molecular_function	structural constituent of chromatin
C	0046982	molecular_function	protein heterodimerization activity
D	0000786	cellular_component	nucleosome
D	0003677	molecular_function	DNA binding
D	0030527	molecular_function	structural constituent of chromatin
D	0046982	molecular_function	protein heterodimerization activity

Functional Information from PROSITE/UniProt

site_id	PS00046
Number of Residues	7
Details	HISTONE_H2A Histone H2A signature. AGLqFPV

Chain	Residue	Details
A	ALA103-VAL109

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site_id	PS00357
Number of Residues	23
Details	HISTONE_H2B Histone H2B signature. REIQTavRlLLpGELaKHAVSEG

Chain	Residue	Details
A	ARG61-GLY83

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	MOD_RES: N6-succinyllysine; alternate => ECO:0000269|PubMed:22389435

Chain	Residue	Details
A	LYS3
D	LYS3
D	LYS85
D	LYS89
A	LYS85
A	LYS89
B	LYS3
B	LYS85
B	LYS89
C	LYS3
C	LYS85
C	LYS89

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	MOD_RES: PolyADP-ribosyl glutamic acid => ECO:0000250|UniProtKB:Q64475

Chain	Residue	Details
A	GLU4
B	GLU4
C	GLU4
D	GLU4

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	MOD_RES: Phosphoserine; by AMPK => ECO:0000250|UniProtKB:Q64524

Chain	Residue	Details
A	SER5
B	SER5
C	SER5
D	SER5

---

site_id	SWS_FT_FI4
Number of Residues	8
Details	MOD_RES: N6-lactoyllysine; alternate => ECO:0000269|PubMed:31645732

Chain	Residue	Details
A	LYS12
A	LYS54
B	LYS12
B	LYS54
C	LYS12
C	LYS54
D	LYS12
D	LYS54

---

site_id	SWS_FT_FI5
Number of Residues	8
Details	MOD_RES: N6-methyllysine; alternate => ECO:0000269|PubMed:16627869

Chain	Residue	Details
A	LYS15
A	LYS77
B	LYS15
B	LYS77
C	LYS15
C	LYS77
D	LYS15
D	LYS77

---

site_id	SWS_FT_FI6
Number of Residues	4
Details	MOD_RES: N6-(2-hydroxyisobutyryl)lysine; alternate => ECO:0000269|PubMed:24681537

Chain	Residue	Details
A	LYS26
B	LYS26
C	LYS26
D	LYS26

---

site_id	SWS_FT_FI7
Number of Residues	4
Details	MOD_RES: Dimethylated arginine => ECO:0000250|UniProtKB:Q96A08

Chain	Residue	Details
A	ARG48
B	ARG48
C	ARG48
D	ARG48

---

site_id	SWS_FT_FI8
Number of Residues	8
Details	MOD_RES: Omega-N-methylarginine => ECO:0000250|UniProtKB:Q96A08

Chain	Residue	Details
A	ARG55
A	ARG61
B	ARG55
B	ARG61
C	ARG55
C	ARG61
D	ARG55
D	ARG61

---

site_id	SWS_FT_FI9
Number of Residues	4
Details	MOD_RES: Phosphothreonine => ECO:0000250|UniProtKB:Q00729

Chain	Residue	Details
A	THR84
B	THR84
C	THR84
D	THR84

---

site_id	SWS_FT_FI10
Number of Residues	4
Details	CARBOHYD: O-linked (GlcNAc) serine => ECO:0000250|UniProtKB:P62807

Chain	Residue	Details
A	SER81
B	SER81
C	SER81
D	SER81

---

site_id	SWS_FT_FI11
Number of Residues	4
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin); alternate => ECO:0000269|PubMed:21726816

Chain	Residue	Details
A	LYS3
B	LYS3
C	LYS3
D	LYS3

---

site_id	SWS_FT_FI12
Number of Residues	8
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin); alternate => ECO:0000269|PubMed:16307923, ECO:0000269|PubMed:16627869, ECO:0000269|PubMed:16713563

Chain	Residue	Details
A	LYS89
B	LYS89
C	LYS89
D	LYS89

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