4NCH

Crystal Structure of Pyrococcus furiosis Rad50 L802W mutation

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0006302	biological_process	double-strand break repair
A	0016887	molecular_function	ATP hydrolysis activity
B	0006302	biological_process	double-strand break repair
B	0016887	molecular_function	ATP hydrolysis activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	10
Details	BINDING SITE FOR RESIDUE SO4 A 901

Chain	Residue
A	ASN32
B	ARG102
A	GLY33
A	SER34
A	GLY35
A	LYS36
A	SER37
A	HOH1014
A	HOH1032
A	HOH1162

---

site_id	AC2
Number of Residues	8
Details	BINDING SITE FOR RESIDUE SO4 A 902

Chain	Residue
A	VAL45
A	PRO50
A	LEU51
A	ARG52
A	ILE53
A	ILE56
A	LYS58
A	HOH1102

---

site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 B 901

Chain	Residue
B	TRP49
B	PRO50
B	LEU51
B	ILE53
B	ILE56
B	LYS58

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	BINDING: BINDING => ECO:0000269|PubMed:10892749, ECO:0000269|PubMed:21441914, ECO:0000269|PubMed:24493214, ECO:0007744|PDB:1F2U, ECO:0007744|PDB:3QKT, ECO:0007744|PDB:3QKU, ECO:0007744|PDB:4NCJ

Chain	Residue	Details
A	ARG12
A	ASN32
A	GLU60
B	ARG12
B	ASN32
B	GLU60

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269|PubMed:10892749, ECO:0000269|PubMed:21441914, ECO:0007744|PDB:1F2U, ECO:0007744|PDB:3QKT, ECO:0007744|PDB:3QKU

Chain	Residue	Details
A	GLN140
B	GLN140

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	BINDING: BINDING => ECO:0000269|PubMed:10892749, ECO:0000269|PubMed:21441914, ECO:0007744|PDB:1F2U, ECO:0007744|PDB:3QKT

Chain	Residue	Details
A	LYS763
A	PHE791
B	LYS763
B	PHE791

---