4NBT
Crystal structure of FabG from Acholeplasma laidlawii
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004316 | molecular_function | 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity |
| A | 0006629 | biological_process | lipid metabolic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0032787 | biological_process | monocarboxylic acid metabolic process |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0004316 | molecular_function | 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity |
| B | 0006629 | biological_process | lipid metabolic process |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0032787 | biological_process | monocarboxylic acid metabolic process |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0004316 | molecular_function | 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity |
| C | 0006629 | biological_process | lipid metabolic process |
| C | 0016491 | molecular_function | oxidoreductase activity |
| C | 0032787 | biological_process | monocarboxylic acid metabolic process |
| D | 0000166 | molecular_function | nucleotide binding |
| D | 0004316 | molecular_function | 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity |
| D | 0006629 | biological_process | lipid metabolic process |
| D | 0016491 | molecular_function | oxidoreductase activity |
| D | 0032787 | biological_process | monocarboxylic acid metabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 31 |
| Details | BINDING SITE FOR RESIDUE NAD A 301 |
| Chain | Residue |
| A | GLY13 |
| A | ASN81 |
| A | ALA82 |
| A | GLY83 |
| A | ILE131 |
| A | SER132 |
| A | SER133 |
| A | TYR146 |
| A | LYS150 |
| A | PRO178 |
| A | GLY179 |
| A | LYS16 |
| A | TYR180 |
| A | ILE181 |
| A | THR183 |
| A | HOH409 |
| A | HOH463 |
| A | HOH473 |
| A | HOH479 |
| A | HOH484 |
| A | HOH535 |
| A | HOH588 |
| A | GLY17 |
| A | HOH626 |
| A | HOH697 |
| A | LEU18 |
| A | ASP37 |
| A | LEU38 |
| A | LEU53 |
| A | ASN54 |
| A | VAL55 |
| site_id | AC2 |
| Number of Residues | 33 |
| Details | BINDING SITE FOR RESIDUE NAD B 301 |
| Chain | Residue |
| B | GLY13 |
| B | LYS16 |
| B | GLY17 |
| B | LEU18 |
| B | ASP37 |
| B | LEU38 |
| B | LEU53 |
| B | ASN54 |
| B | VAL55 |
| B | ASN81 |
| B | ALA82 |
| B | GLY83 |
| B | ILE84 |
| B | ILE131 |
| B | SER132 |
| B | SER133 |
| B | TYR146 |
| B | LYS150 |
| B | PRO178 |
| B | GLY179 |
| B | ILE181 |
| B | THR183 |
| B | HOH408 |
| B | HOH480 |
| B | HOH504 |
| B | HOH532 |
| B | HOH558 |
| B | HOH561 |
| B | HOH635 |
| B | HOH654 |
| B | HOH657 |
| B | HOH658 |
| B | HOH663 |
| site_id | AC3 |
| Number of Residues | 33 |
| Details | BINDING SITE FOR RESIDUE NAD C 301 |
| Chain | Residue |
| C | GLY13 |
| C | LYS16 |
| C | GLY17 |
| C | LEU18 |
| C | ASP37 |
| C | LEU38 |
| C | LEU53 |
| C | ASN54 |
| C | VAL55 |
| C | ASN81 |
| C | ALA82 |
| C | GLY83 |
| C | ILE131 |
| C | SER132 |
| C | SER133 |
| C | TYR146 |
| C | LYS150 |
| C | PRO178 |
| C | GLY179 |
| C | TYR180 |
| C | ILE181 |
| C | THR183 |
| C | ASP184 |
| C | ILE185 |
| C | HOH405 |
| C | HOH406 |
| C | HOH411 |
| C | HOH412 |
| C | HOH429 |
| C | HOH453 |
| C | HOH470 |
| C | HOH474 |
| C | HOH582 |
| site_id | AC4 |
| Number of Residues | 32 |
| Details | BINDING SITE FOR RESIDUE NAD D 301 |
| Chain | Residue |
| D | GLY17 |
| D | LEU18 |
| D | ASP37 |
| D | LEU38 |
| D | LEU53 |
| D | ASN54 |
| D | VAL55 |
| D | ASN81 |
| D | ALA82 |
| D | GLY83 |
| D | ILE131 |
| D | SER132 |
| D | SER133 |
| D | TYR146 |
| D | LYS150 |
| D | PRO178 |
| D | GLY179 |
| D | TYR180 |
| D | ILE181 |
| D | THR183 |
| D | ILE185 |
| D | HOH418 |
| D | HOH425 |
| D | HOH428 |
| D | HOH437 |
| D | HOH467 |
| D | HOH486 |
| D | HOH492 |
| D | HOH522 |
| D | HOH669 |
| D | GLY13 |
| D | LYS16 |
Functional Information from PROSITE/UniProt
| site_id | PS00061 |
| Number of Residues | 29 |
| Details | ADH_SHORT Short-chain dehydrogenases/reductases family signature. SvvgvfgnigQanYAATKAGViGLTmTWA |
| Chain | Residue | Details |
| A | SER133-ALA161 |
