Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0008299 | biological_process | isoprenoid biosynthetic process |
| A | 0050518 | molecular_function | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity |
| A | 0070567 | molecular_function | cytidylyltransferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE PBQ A 401 |
| Chain | Residue |
| A | ALA203 |
| A | GLN238 |
| A | VAL239 |
| A | LEU245 |
| A | SER264 |
| A | ILE265 |
| A | VAL266 |
| A | CD403 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE DTT A 402 |
| Chain | Residue |
| A | ASP196 |
| A | ALA199 |
| A | VAL200 |
| A | TYR274 |
| A | K409 |
| A | K409 |
| A | K409 |
| A | LYS195 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CD A 403 |
| Chain | Residue |
| A | GLN238 |
| A | PBQ401 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CD A 404 |
| Chain | Residue |
| A | GLU167 |
| A | GLU167 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CD A 405 |
| Chain | Residue |
| A | ASP261 |
| A | HOH517 |
| A | HOH526 |
| A | HOH560 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CD A 406 |
| Chain | Residue |
| A | GLU138 |
| A | GLU141 |
| A | ASP169 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CD A 407 |
| Chain | Residue |
| A | GLU121 |
| A | GLU191 |
| A | HIS271 |
| A | HOH507 |
| A | HOH539 |
| site_id | AC8 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE K A 408 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE K A 409 |
| Chain | Residue |
| A | DTT402 |
| A | DTT402 |
| A | DTT402 |
| site_id | BC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE K A 410 |
| Chain | Residue |
| A | ARG182 |
| A | PRO183 |
| A | LEU184 |
| A | ASN282 |
| A | ILE283 |
| site_id | BC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE K A 411 |
| Chain | Residue |
| A | ILE108 |
| A | ALA109 |
| A | SER112 |
| A | SER180 |
| A | PRO183 |
| site_id | BC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE K A 412 |
| Chain | Residue |
| A | SER117 |
| A | MET119 |
| A | VAL122 |
| A | ASP145 |
| A | VAL146 |
| site_id | BC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE K A 413 |
| Chain | Residue |
| A | ASN186 |
| A | ASP189 |
| A | HOH505 |
| A | HOH508 |
Functional Information from PROSITE/UniProt
| site_id | PS01295 |
| Number of Residues | 8 |
| Details | ISPD 4-diphosphocytidyl-2C-methyl-D-erythritol synthase signature. VCIHDSAR |
| Chain | Residue | Details |
| A | VAL175-ARG182 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | SITE: Transition state stabilizer => ECO:0000250 |
| Chain | Residue | Details |
| A | ARG91 | |
| A | LYS98 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | SITE: Positions MEP for the nucleophilic attack => ECO:0000250 |
| Chain | Residue | Details |
| A | ARG228 | |
| A | LYS284 | |
