4NA5

Crystal structure of mouse poly(ADP-ribose) glycohydrolase (PARG) catalytic domain mutant E748N

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004649	molecular_function	poly(ADP-ribose) glycohydrolase activity
A	0005975	biological_process	carbohydrate metabolic process
A	0006282	biological_process	regulation of DNA repair

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 A 1001

Chain	Residue
A	ARG528
A	ARG637
A	ASN639
A	HOH1214
A	HOH1436

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site_id	AC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 A 1002

Chain	Residue
A	LYS444
A	ARG902

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site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 A 1003

Chain	Residue
A	HOH1326
A	HOH1327
A	SER466
A	ARG468

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site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 A 1004

Chain	Residue
A	SER644
A	GLU645
A	HOH1303
A	HOH1450

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	ACT_SITE: ACT_SITE => ECO:0000250|UniProtKB:Q86W56

Chain	Residue	Details
A	ASP730
A	ASN748
A	GLU749

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site_id	SWS_FT_FI2
Number of Residues	4
Details	BINDING: BINDING => ECO:0000250|UniProtKB:Q86W56

Chain	Residue	Details
A	ILE719
A	ASN733
A	GLN747
A	ASN862

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	BINDING: BINDING => ECO:0000250|UniProtKB:Q9QYM2

Chain	Residue	Details
A	TYR788

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