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4N6V

Partial rotational order disorder structure of human stefin B

Functional Information from GO Data
ChainGOidnamespacecontents
00002020molecular_functionprotease binding
00003723molecular_functionRNA binding
00004866molecular_functionendopeptidase inhibitor activity
00004869molecular_functioncysteine-type endopeptidase inhibitor activity
00005576cellular_componentextracellular region
00005615cellular_componentextracellular space
00005634cellular_componentnucleus
00005730cellular_componentnucleolus
00005737cellular_componentcytoplasm
00005829cellular_componentcytosol
00008344biological_processadult locomotory behavior
00030414molecular_functionpeptidase inhibitor activity
00031012cellular_componentextracellular matrix
00034774cellular_componentsecretory granule lumen
00045861biological_processnegative regulation of proteolysis
00070062cellular_componentextracellular exosome
01904724cellular_componenttertiary granule lumen
01904813cellular_componentficolin-1-rich granule lumen
10002020molecular_functionprotease binding
10003723molecular_functionRNA binding
10004866molecular_functionendopeptidase inhibitor activity
10004869molecular_functioncysteine-type endopeptidase inhibitor activity
10005576cellular_componentextracellular region
10005615cellular_componentextracellular space
10005634cellular_componentnucleus
10005730cellular_componentnucleolus
10005737cellular_componentcytoplasm
10005829cellular_componentcytosol
10008344biological_processadult locomotory behavior
10030414molecular_functionpeptidase inhibitor activity
10031012cellular_componentextracellular matrix
10034774cellular_componentsecretory granule lumen
10045861biological_processnegative regulation of proteolysis
10070062cellular_componentextracellular exosome
11904724cellular_componenttertiary granule lumen
11904813cellular_componentficolin-1-rich granule lumen
20002020molecular_functionprotease binding
20003723molecular_functionRNA binding
20004866molecular_functionendopeptidase inhibitor activity
20004869molecular_functioncysteine-type endopeptidase inhibitor activity
20005576cellular_componentextracellular region
20005615cellular_componentextracellular space
20005634cellular_componentnucleus
20005730cellular_componentnucleolus
20005737cellular_componentcytoplasm
20005829cellular_componentcytosol
20008344biological_processadult locomotory behavior
20030414molecular_functionpeptidase inhibitor activity
20031012cellular_componentextracellular matrix
20034774cellular_componentsecretory granule lumen
20045861biological_processnegative regulation of proteolysis
20070062cellular_componentextracellular exosome
21904724cellular_componenttertiary granule lumen
21904813cellular_componentficolin-1-rich granule lumen
30002020molecular_functionprotease binding
30003723molecular_functionRNA binding
30004866molecular_functionendopeptidase inhibitor activity
30004869molecular_functioncysteine-type endopeptidase inhibitor activity
30005576cellular_componentextracellular region
30005615cellular_componentextracellular space
30005634cellular_componentnucleus
30005730cellular_componentnucleolus
30005737cellular_componentcytoplasm
30005829cellular_componentcytosol
30008344biological_processadult locomotory behavior
30030414molecular_functionpeptidase inhibitor activity
30031012cellular_componentextracellular matrix
30034774cellular_componentsecretory granule lumen
30045861biological_processnegative regulation of proteolysis
30070062cellular_componentextracellular exosome
31904724cellular_componenttertiary granule lumen
31904813cellular_componentficolin-1-rich granule lumen
40002020molecular_functionprotease binding
40003723molecular_functionRNA binding
40004866molecular_functionendopeptidase inhibitor activity
40004869molecular_functioncysteine-type endopeptidase inhibitor activity
40005576cellular_componentextracellular region
40005615cellular_componentextracellular space
40005634cellular_componentnucleus
40005730cellular_componentnucleolus
40005737cellular_componentcytoplasm
40005829cellular_componentcytosol
40008344biological_processadult locomotory behavior
40030414molecular_functionpeptidase inhibitor activity
40031012cellular_componentextracellular matrix
40034774cellular_componentsecretory granule lumen
40045861biological_processnegative regulation of proteolysis
40070062cellular_componentextracellular exosome
41904724cellular_componenttertiary granule lumen
41904813cellular_componentficolin-1-rich granule lumen
50002020molecular_functionprotease binding
50003723molecular_functionRNA binding
50004866molecular_functionendopeptidase inhibitor activity
50004869molecular_functioncysteine-type endopeptidase inhibitor activity
50005576cellular_componentextracellular region
50005615cellular_componentextracellular space
50005634cellular_componentnucleus
50005730cellular_componentnucleolus
50005737cellular_componentcytoplasm
50005829cellular_componentcytosol
50008344biological_processadult locomotory behavior
50030414molecular_functionpeptidase inhibitor activity
50031012cellular_componentextracellular matrix
50034774cellular_componentsecretory granule lumen
50045861biological_processnegative regulation of proteolysis
50070062cellular_componentextracellular exosome
51904724cellular_componenttertiary granule lumen
51904813cellular_componentficolin-1-rich granule lumen
60002020molecular_functionprotease binding
60003723molecular_functionRNA binding
60004866molecular_functionendopeptidase inhibitor activity
60004869molecular_functioncysteine-type endopeptidase inhibitor activity
60005576cellular_componentextracellular region
60005615cellular_componentextracellular space
60005634cellular_componentnucleus
60005730cellular_componentnucleolus
60005737cellular_componentcytoplasm
60005829cellular_componentcytosol
60008344biological_processadult locomotory behavior
60030414molecular_functionpeptidase inhibitor activity
60031012cellular_componentextracellular matrix
60034774cellular_componentsecretory granule lumen
60045861biological_processnegative regulation of proteolysis
60070062cellular_componentextracellular exosome
61904724cellular_componenttertiary granule lumen
61904813cellular_componentficolin-1-rich granule lumen
70002020molecular_functionprotease binding
70003723molecular_functionRNA binding
70004866molecular_functionendopeptidase inhibitor activity
70004869molecular_functioncysteine-type endopeptidase inhibitor activity
70005576cellular_componentextracellular region
70005615cellular_componentextracellular space
70005634cellular_componentnucleus
70005730cellular_componentnucleolus
70005737cellular_componentcytoplasm
70005829cellular_componentcytosol
70008344biological_processadult locomotory behavior
70030414molecular_functionpeptidase inhibitor activity
70031012cellular_componentextracellular matrix
70034774cellular_componentsecretory granule lumen
70045861biological_processnegative regulation of proteolysis
70070062cellular_componentextracellular exosome
71904724cellular_componenttertiary granule lumen
71904813cellular_componentficolin-1-rich granule lumen
80002020molecular_functionprotease binding
80003723molecular_functionRNA binding
80004866molecular_functionendopeptidase inhibitor activity
80004869molecular_functioncysteine-type endopeptidase inhibitor activity
80005576cellular_componentextracellular region
80005615cellular_componentextracellular space
80005634cellular_componentnucleus
80005730cellular_componentnucleolus
80005737cellular_componentcytoplasm
80005829cellular_componentcytosol
80008344biological_processadult locomotory behavior
80030414molecular_functionpeptidase inhibitor activity
80031012cellular_componentextracellular matrix
80034774cellular_componentsecretory granule lumen
80045861biological_processnegative regulation of proteolysis
80070062cellular_componentextracellular exosome
81904724cellular_componenttertiary granule lumen
81904813cellular_componentficolin-1-rich granule lumen
90002020molecular_functionprotease binding
90003723molecular_functionRNA binding
90004866molecular_functionendopeptidase inhibitor activity
90004869molecular_functioncysteine-type endopeptidase inhibitor activity
90005576cellular_componentextracellular region
90005615cellular_componentextracellular space
90005634cellular_componentnucleus
90005730cellular_componentnucleolus
90005737cellular_componentcytoplasm
90005829cellular_componentcytosol
90008344biological_processadult locomotory behavior
90030414molecular_functionpeptidase inhibitor activity
90031012cellular_componentextracellular matrix
90034774cellular_componentsecretory granule lumen
90045861biological_processnegative regulation of proteolysis
90070062cellular_componentextracellular exosome
91904724cellular_componenttertiary granule lumen
91904813cellular_componentficolin-1-rich granule lumen
Functional Information from PDB Data
site_idAC1
Number of Residues7
DetailsBINDING SITE FOR RESIDUE SO4 2 101
ChainResidue
2ALA8
2THR9
2LYS44
2GLN46
2TYR97
2HOH273
2HOH274

site_idAC2
Number of Residues7
DetailsBINDING SITE FOR RESIDUE SO4 1 101
ChainResidue
1LYS44
1GLN46
1TYR97
1HOH204
1HOH205
1ALA8
1THR9

site_idAC3
Number of Residues7
DetailsBINDING SITE FOR RESIDUE SO4 9 101
ChainResidue
9ALA8
9THR9
9LYS44
9GLN46
9TYR97
9HOH202
9HOH204

site_idAC4
Number of Residues7
DetailsBINDING SITE FOR RESIDUE SO4 8 101
ChainResidue
8ALA8
8THR9
8LYS44
8GLN46
8TYR97
8HOH206
8HOH275

Functional Information from PROSITE/UniProt
site_idPS00287
Number of Residues14
DetailsCYSTATIN Cysteine proteases inhibitors signature. SQVVAGTNYfIKVH
ChainResidueDetails
2SER45-HIS58

237992

PDB entries from 2025-06-25

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