4N65
Crystal structure of paAzoR1 bound to anthraquinone-2-sulphonate
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003960 | molecular_function | quinone reductase (NADPH) activity |
| A | 0006979 | biological_process | response to oxidative stress |
| A | 0009055 | molecular_function | electron transfer activity |
| A | 0010181 | molecular_function | FMN binding |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016652 | molecular_function | oxidoreductase activity, acting on NAD(P)H as acceptor |
| A | 0016655 | molecular_function | oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor |
| B | 0003960 | molecular_function | quinone reductase (NADPH) activity |
| B | 0006979 | biological_process | response to oxidative stress |
| B | 0009055 | molecular_function | electron transfer activity |
| B | 0010181 | molecular_function | FMN binding |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0016652 | molecular_function | oxidoreductase activity, acting on NAD(P)H as acceptor |
| B | 0016655 | molecular_function | oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE FMN A 301 |
| Chain | Residue |
| A | SER10 |
| A | PHE100 |
| A | SER145 |
| A | ARG146 |
| A | GLY147 |
| A | GLY148 |
| A | PHE151 |
| A | GLU187 |
| A | GLU188 |
| A | HOH407 |
| A | HOH415 |
| A | ARG12 |
| B | VAL56 |
| A | SER16 |
| A | GLN17 |
| A | SER18 |
| A | PRO96 |
| A | MET97 |
| A | TYR98 |
| A | ASN99 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE AQN A 302 |
| Chain | Residue |
| A | TYR131 |
| A | PHE173 |
| A | HOH514 |
| A | HOH531 |
| B | PHE100 |
| B | GLY147 |
| B | GLY148 |
| B | FMN301 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 A 303 |
| Chain | Residue |
| A | ARG30 |
| A | ARG40 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 304 |
| Chain | Residue |
| A | ARG139 |
| A | LEU208 |
| A | ALA212 |
| A | HOH459 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 A 305 |
| Chain | Residue |
| A | LEU48 |
| A | ALA50 |
| A | SER104 |
| A | GLY105 |
| A | HOH440 |
| B | LEU48 |
| B | SER104 |
| B | GLY105 |
| site_id | AC6 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE FMN B 301 |
| Chain | Residue |
| A | PHE60 |
| A | AQN302 |
| B | SER10 |
| B | ARG12 |
| B | SER16 |
| B | GLN17 |
| B | SER18 |
| B | PRO96 |
| B | MET97 |
| B | TYR98 |
| B | ASN99 |
| B | PHE100 |
| B | SER145 |
| B | ARG146 |
| B | GLY147 |
| B | GLY148 |
| B | PHE151 |
| B | HOH414 |
| B | HOH424 |
| B | HOH487 |
| B | HOH516 |
| site_id | AC7 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE GOL B 302 |
| Chain | Residue |
| B | ALA50 |
| B | VAL51 |
| B | THR52 |
| B | PHE55 |
| B | ASP74 |
| B | GLN112 |
| B | HOH404 |
| B | HOH412 |
| B | HOH437 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 18 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01216","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"17904577","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"20057057","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"20417637","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22355582","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24915188","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2V9C","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3KEG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3LT5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3R6W","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N65","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N9Q","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"20417637","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"22355582","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"3LT5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3R6W","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"20417637","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22355582","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24915188","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3LT5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3R6W","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N65","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N9Q","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"20057057","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"20417637","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"3KEG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3LT5","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Site: {"description":"Important in the architecture of the active site","evidences":[{"source":"PubMed","id":"20057057","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
