4N0Z

Crystal structure of cisplatin bound to a plasmodium falciparum glutaredoxin 1 (PfGrx1)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0015038	molecular_function	glutathione disulfide oxidoreductase activity
A	0016209	molecular_function	antioxidant activity
A	0016491	molecular_function	oxidoreductase activity
A	0019153	molecular_function	protein-disulfide reductase (glutathione) activity
A	0046872	molecular_function	metal ion binding
A	0098869	biological_process	cellular oxidant detoxification

Functional Information from PDB Data

site_id	AC1
Number of Residues	12
Details	BINDING SITE FOR RESIDUE MPO A 201

Chain	Residue
A	SER5
A	HOH301
A	HOH311
A	HOH346
A	LYS9
A	TYR31
A	TYR65
A	GLU68
A	PRO76
A	GLY87
A	CYS88
A	ASP89

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site_id	AC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MPD A 202

Chain	Residue
A	ASN13
A	LYS82

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site_id	AC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE CPT A 203

Chain	Residue
A	ASN19
A	MET48
A	HIS49
A	LYS67
A	GLU68
A	HOH381
A	HOH406

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Functional Information from PROSITE/UniProt

site_id	PS00195
Number of Residues	17
Details	GLUTAREDOXIN_1 Glutaredoxin active site. VFakteCPYCikAisiL

Chain	Residue	Details
A	VAL23-LEU39

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