4MZY

Crystal structure of enterococcus faecalis nicotinate phosphoribosyltransferase with malonate and phosphate bound

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004516	molecular_function	nicotinate phosphoribosyltransferase activity
A	0005829	cellular_component	cytosol
A	0009435	biological_process	NAD biosynthetic process
A	0016757	molecular_function	glycosyltransferase activity
A	0016874	molecular_function	ligase activity
A	0019363	biological_process	pyridine nucleotide biosynthetic process
A	0034355	biological_process	NAD salvage

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE PO4 A 501

Chain	Residue
A	HIS225
A	ARG226
A	ASP227
A	HOH725
A	HOH726

---

site_id	AC2
Number of Residues	9
Details	BINDING SITE FOR RESIDUE PO4 A 502

Chain	Residue
A	THR317
A	HOH630
A	HOH654
A	HOH722
A	HOH723
A	PHE160
A	ASN293
A	ASP294
A	GLY316

---

site_id	AC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL A 503

Chain	Residue
A	TYR179
A	ILE180
A	GLY181
A	GLY182
A	LYS437
A	LEU444
A	HOH685

---

site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL A 504

Chain	Residue
A	GLU104
A	TYR428
A	PRO431
A	TYR439
A	HOH666

---

site_id	AC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL A 505

Chain	Residue
A	MET396
A	HIS398
A	LYS406
A	PRO461
A	ASP463
A	GOL513

---

site_id	AC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL A 506

Chain	Residue
A	SER150
A	ARG453
A	ASP454
A	LEU455

---

site_id	AC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL A 507

Chain	Residue
A	ASP236
A	LEU238
A	LYS239
A	HOH658

---

site_id	AC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL A 508

Chain	Residue
A	ASP85
A	GLN364
A	TRP384
A	GLU386
A	ASP387
A	ARG389

---

site_id	AC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL A 509

Chain	Residue
A	GLY212
A	ASN213
A	LEU486
A	HOH631
A	HOH758

---

site_id	BC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE GOL A 510

Chain	Residue
A	LYS149
A	ASP154
A	ASP184

---

site_id	BC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL A 511

Chain	Residue
A	ASP7
A	GLU57
A	ASN61
A	ILE194
A	MLA516
A	HOH690
A	HOH732

---

site_id	BC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL A 512

Chain	Residue
A	LEU63
A	GLU64
A	LEU66
A	GLU94
A	PHE95
A	LYS255

---

site_id	BC4
Number of Residues	10
Details	BINDING SITE FOR RESIDUE GOL A 513

Chain	Residue
A	TYR270
A	HIS398
A	LYS459
A	TYR460
A	PRO461
A	VAL462
A	ASP463
A	GOL505
A	HOH673
A	HOH701

---

site_id	BC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE GOL A 514

Chain	Residue
A	ASP155
A	ILE310
A	ASP311

---

site_id	BC6
Number of Residues	9
Details	BINDING SITE FOR RESIDUE MLA A 515

Chain	Residue
A	GLN125
A	GLU128
A	ALA204
A	HIS205
A	SER206
A	LYS333
A	FMT520
A	HOH626
A	HOH721

---

site_id	BC7
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MLA A 516

Chain	Residue
A	ASP7
A	ARG58
A	ASP169
A	TRP173
A	ARG190
A	GOL511
A	HOH759

---

site_id	BC8
Number of Residues	8
Details	BINDING SITE FOR RESIDUE MLA A 517

Chain	Residue
A	THR359
A	LYS363
A	HOH714
A	HOH730
A	HOH761
A	GLU38
A	TYR40
A	PRO113

---

site_id	BC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL A 518

Chain	Residue
A	ARG163
A	ARG164
A	VAL331
A	PHE332

---

site_id	CC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL A 519

Chain	Residue
A	ARG274

---

site_id	CC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE FMT A 520

Chain	Residue
A	PHE160
A	ARG262
A	MLA515

---

site_id	CC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL A 521

Chain	Residue
A	THR202
A	HOH638
A	HOH768
A	HOH769

---

site_id	CC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL A 522

Chain	Residue
A	SER200
A	GLY201
A	HOH767
A	HOH768

---