4MYO

Crystal structure of streptogramin group A antibiotic acetyltransferase VatA from Staphylococcus aureus

Replaces:  4E8L

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016740	molecular_function	transferase activity
A	0016746	molecular_function	acyltransferase activity
A	0046677	biological_process	response to antibiotic
B	0016740	molecular_function	transferase activity
B	0016746	molecular_function	acyltransferase activity
B	0046677	biological_process	response to antibiotic
C	0016740	molecular_function	transferase activity
C	0016746	molecular_function	acyltransferase activity
C	0046677	biological_process	response to antibiotic

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG A 301

Chain	Residue
A	ASN164
A	HOH432
B	ASN164
B	HOH429
B	HOH430
C	ASN164

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site_id	AC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL A 302

Chain	Residue
A	LYS153
A	PHE168

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site_id	AC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL A 303

Chain	Residue
A	ASN203

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site_id	AC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL A 304

Chain	Residue
A	GLU60

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site_id	AC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL A 305

Chain	Residue
A	ASP118
A	LYS138

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site_id	AC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL B 302

Chain	Residue
B	PHE168

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site_id	AC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL B 304

Chain	Residue
B	ARG88

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site_id	AC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 B 305

Chain	Residue
B	LYS27
B	GLY38
B	GLU39
B	ARG70

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site_id	AC9
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL C 301

Chain	Residue
C	ARG100

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site_id	BC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 C 304

Chain	Residue
C	LYS27
C	GLY38
C	GLU39
C	ARG70

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site_id	BC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 C 305

Chain	Residue
C	LYS153
C	PHE168

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Functional Information from PROSITE/UniProt

site_id	PS00101
Number of Residues	29
Details	HEXAPEP_TRANSFERASES Hexapeptide-repeat containing-transferases signature. IGrdVtImpgVkIGdgAiIAaeAvVtknV

Chain	Residue	Details
A	ILE127-VAL155

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	Active site: {"evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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