4MU8
Crystal structure of an oxidized form of yeast iso-1-cytochrome c at pH 8.8
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005515 | molecular_function | protein binding |
| A | 0005739 | cellular_component | mitochondrion |
| A | 0005758 | cellular_component | mitochondrial intermembrane space |
| A | 0006122 | biological_process | mitochondrial electron transport, ubiquinol to cytochrome c |
| A | 0006123 | biological_process | mitochondrial electron transport, cytochrome c to oxygen |
| A | 0009055 | molecular_function | electron transfer activity |
| A | 0020037 | molecular_function | heme binding |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0070469 | cellular_component | respirasome |
| A | 1901612 | molecular_function | cardiolipin binding |
| B | 0005515 | molecular_function | protein binding |
| B | 0005739 | cellular_component | mitochondrion |
| B | 0005758 | cellular_component | mitochondrial intermembrane space |
| B | 0006122 | biological_process | mitochondrial electron transport, ubiquinol to cytochrome c |
| B | 0006123 | biological_process | mitochondrial electron transport, cytochrome c to oxygen |
| B | 0009055 | molecular_function | electron transfer activity |
| B | 0020037 | molecular_function | heme binding |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0070469 | cellular_component | respirasome |
| B | 1901612 | molecular_function | cardiolipin binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE HEC A 201 |
| Chain | Residue |
| A | ARG13 |
| A | TYR46 |
| A | TYR48 |
| A | THR49 |
| A | ASN52 |
| A | TRP59 |
| A | MET64 |
| A | TYR67 |
| A | LEU68 |
| A | THR78 |
| A | LYS79 |
| A | CYS14 |
| A | MET80 |
| A | PHE82 |
| A | LEU85 |
| A | HOH303 |
| A | HOH304 |
| A | CYS17 |
| A | HIS18 |
| A | GLY29 |
| A | PRO30 |
| A | ILE35 |
| A | SER40 |
| A | GLY41 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 202 |
| Chain | Residue |
| A | THR49 |
| A | ASP50 |
| A | HOH310 |
| A | HOH343 |
| A | HOH386 |
| A | HOH433 |
| site_id | AC3 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE SO4 A 203 |
| Chain | Residue |
| A | LYS79 |
| A | LYS79 |
| A | LYS79 |
| A | MET80 |
| A | MET80 |
| A | MET80 |
| A | HOH308 |
| A | HOH308 |
| A | HOH308 |
| A | HOH376 |
| A | HOH376 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 204 |
| Chain | Residue |
| A | SER2 |
| A | ALA3 |
| A | LYS4 |
| A | HOH353 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 205 |
| Chain | Residue |
| A | LYS86 |
| A | LYS87 |
| A | GLU88 |
| A | HOH349 |
| A | HOH438 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE TBU A 206 |
| Chain | Residue |
| A | GLN16 |
| A | GLN16 |
| A | GLN16 |
| A | CYS17 |
| A | CYS17 |
| A | CYS17 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 B 201 |
| Chain | Residue |
| A | ARG38 |
| A | HOH490 |
| B | SER2 |
| B | ALA3 |
| B | LYS4 |
| B | HOH302 |
| B | HOH316 |
| site_id | AC8 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE HEC B 202 |
| Chain | Residue |
| B | ARG13 |
| B | CYS14 |
| B | CYS17 |
| B | HIS18 |
| B | GLY29 |
| B | PRO30 |
| B | ILE35 |
| B | SER40 |
| B | GLY41 |
| B | TYR46 |
| B | TYR48 |
| B | THR49 |
| B | ASN52 |
| B | TRP59 |
| B | MET64 |
| B | TYR67 |
| B | LEU68 |
| B | THR78 |
| B | LYS79 |
| B | MET80 |
| B | PHE82 |
| B | HOH305 |
| B | HOH306 |
| B | HOH318 |
| site_id | AC9 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE SO4 B 203 |
| Chain | Residue |
| B | LYS79 |
| B | LYS79 |
| B | LYS79 |
| B | MET80 |
| B | MET80 |
| B | MET80 |
| B | HOH307 |
| B | HOH307 |
| B | HOH307 |
| B | HOH372 |
| B | HOH372 |
| B | HOH372 |
| site_id | BC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 B 204 |
| Chain | Residue |
| B | THR49 |
| B | ASP50 |
| B | HOH312 |
| B | HOH355 |
| B | HOH359 |
| B | HOH402 |
| site_id | BC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 B 205 |
| Chain | Residue |
| B | GLU88 |
| B | HOH356 |
| B | HOH432 |
| site_id | BC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL B 206 |
| Chain | Residue |
| A | HOH316 |
| B | GLU61 |
| B | ASN62 |
| B | GLU66 |
| B | TYR74 |
| B | HOH317 |
| B | HOH324 |
| site_id | BC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE TBU B 207 |
| Chain | Residue |
| B | GLN16 |
| B | GLN16 |
| B | GLN16 |
| B | CYS17 |
| B | CYS17 |
| B | CYS17 |
| site_id | BC5 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE TBU B 208 |
| Chain | Residue |
| A | ALA51 |
| A | LYS54 |
| A | LYS55 |
| A | PRO76 |
| B | ALA51 |
| B | LYS54 |
| B | LYS55 |
| B | ILE75 |
| B | PRO76 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | BINDING: covalent => ECO:0000269|PubMed:11880631, ECO:0000269|PubMed:18390544, ECO:0007744|PDB:1KYO, ECO:0007744|PDB:3CX5 |
| Chain | Residue | Details |
| A | CYS14 | |
| A | CYS17 | |
| B | CYS14 | |
| B | CYS17 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | BINDING: axial binding residue => ECO:0000269|PubMed:11880631, ECO:0000269|PubMed:18390544, ECO:0007744|PDB:1KYO, ECO:0007744|PDB:3CX5 |
| Chain | Residue | Details |
| A | HIS18 | |
| A | MET80 | |
| B | HIS18 | |
| B | MET80 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | MOD_RES: N6,N6,N6-trimethyllysine; by CTM1 => ECO:0000269|PubMed:10791961, ECO:0000269|PubMed:11880631, ECO:0007744|PDB:1KYO |
| Chain | Residue | Details |
| A | ALA72 | |
| B | ALA72 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | MOD_RES: N6,N6,N6-trimethyllysine => ECO:0000269|PubMed:10821864, ECO:0000269|PubMed:18390544 |
| Chain | Residue | Details |
| A | LYS73 | |
| B | LYS73 |
