4MSW

Y78 ester mutant of KcsA in high K+

Functional Information from GO Data

Chain	GOid	namespace	contents
B	0002250	biological_process	adaptive immune response
B	0002376	biological_process	immune system process
B	0005576	cellular_component	extracellular region
B	0005886	cellular_component	plasma membrane
B	0019814	cellular_component	immunoglobulin complex
C	0005249	molecular_function	voltage-gated potassium channel activity
C	0006813	biological_process	potassium ion transport
C	0008076	cellular_component	voltage-gated potassium channel complex

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE DGA C 1001

Chain	Residue
A	THR30
B	GLU53
C	PRO63
C	LEU85
C	HOH1113

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site_id	AC3
Number of Residues	12
Details	BINDING SITE FOR RESIDUE K C 1003

Chain	Residue
C	VAL76
C	VAL76
C	VAL76
C	VAL76
C	K1004
C	K1004
C	K1004
C	K1004
C	THR75
C	THR75
C	THR75
C	THR75

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site_id	AC4
Number of Residues	8
Details	BINDING SITE FOR RESIDUE K C 1004

Chain	Residue
C	THR75
C	THR75
C	THR75
C	THR75
C	K1003
C	K1003
C	K1003
C	K1003

---

site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE K C 1006

Chain	Residue
C	K1007
C	K1007
C	K1007
C	K1007

---

site_id	AC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE K C 1007

Chain	Residue
C	K1006
C	K1006
C	K1006
C	K1006

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Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YTCEATH

Chain	Residue	Details
B	TYR192-HIS198

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI2
Number of Residues	45
Details	Transmembrane: {"description":"Helical"}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	16
Details	Topological domain: {"description":"Extracellular"}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	10
Details	Intramembrane: {"description":"Helical; Pore-forming"}

Chain

Residue

Details

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