4MS2
Structural basis of Ca2+ selectivity of a voltage-gated calcium channel
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005216 | molecular_function | monoatomic ion channel activity |
| A | 0005261 | molecular_function | monoatomic cation channel activity |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006811 | biological_process | monoatomic ion transport |
| A | 0016020 | cellular_component | membrane |
| A | 0055085 | biological_process | transmembrane transport |
| B | 0005216 | molecular_function | monoatomic ion channel activity |
| B | 0005261 | molecular_function | monoatomic cation channel activity |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0006811 | biological_process | monoatomic ion transport |
| B | 0016020 | cellular_component | membrane |
| B | 0055085 | biological_process | transmembrane transport |
| C | 0005216 | molecular_function | monoatomic ion channel activity |
| C | 0005261 | molecular_function | monoatomic cation channel activity |
| C | 0005886 | cellular_component | plasma membrane |
| C | 0006811 | biological_process | monoatomic ion transport |
| C | 0016020 | cellular_component | membrane |
| C | 0055085 | biological_process | transmembrane transport |
| D | 0005216 | molecular_function | monoatomic ion channel activity |
| D | 0005261 | molecular_function | monoatomic cation channel activity |
| D | 0005886 | cellular_component | plasma membrane |
| D | 0006811 | biological_process | monoatomic ion transport |
| D | 0016020 | cellular_component | membrane |
| D | 0055085 | biological_process | transmembrane transport |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PX4 A 1301 |
| Chain | Residue |
| A | PRO1075 |
| A | TRP1076 |
| A | SER1121 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE CA A 1302 |
| Chain | Residue |
| D | HOH1401 |
| D | HOH1402 |
| A | HOH1401 |
| A | HOH1402 |
| B | HOH1401 |
| B | HOH1402 |
| C | HOH1401 |
| C | HOH1402 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CA A 1303 |
| Chain | Residue |
| A | HOH1406 |
| B | HOH1405 |
| C | HOH1405 |
| D | HOH1406 |
| site_id | AC4 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CA A 1304 |
| Chain | Residue |
| D | CA1303 |
| site_id | AC5 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE PX4 A 1305 |
| Chain | Residue |
| A | GLY1026 |
| A | ILE1027 |
| A | GLY1030 |
| A | SER1034 |
| C | THR1138 |
| C | TYR1142 |
| C | THR1162 |
| C | LEU1163 |
| C | GLY1164 |
| C | PX41303 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PX4 A 1306 |
| Chain | Residue |
| A | MET1188 |
| A | TRP1195 |
| B | GLY1164 |
| B | GLU1165 |
| D | PX41304 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PX4 A 1307 |
| Chain | Residue |
| A | PHE1144 |
| A | MET1147 |
| A | LEU1151 |
| A | ARG1155 |
| A | TYR1191 |
| A | TYR1193 |
| B | ILE1097 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PX4 B 1301 |
| Chain | Residue |
| B | PRO1075 |
| B | TRP1076 |
| B | SER1121 |
| B | ILE1124 |
| site_id | AC9 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE PX4 B 1302 |
| Chain | Residue |
| A | LEU1139 |
| A | TYR1142 |
| A | GLY1164 |
| B | GLY1026 |
| B | GLY1030 |
| B | SER1034 |
| B | THR1036 |
| C | PX41304 |
| site_id | BC1 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE PX4 B 1303 |
| Chain | Residue |
| B | MET1188 |
| B | TRP1195 |
| B | ILE1199 |
| B | PHE1203 |
| B | PX41306 |
| C | PX41302 |
| D | GLY1164 |
| D | GLU1165 |
| D | MET1209 |
| site_id | BC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE PX4 B 1304 |
| Chain | Residue |
| B | LEU1151 |
| B | ARG1155 |
| B | VAL1190 |
| B | TYR1191 |
| B | TYR1193 |
| B | ALA1194 |
| B | VAL1196 |
| D | ILE1097 |
| site_id | BC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PX4 B 1305 |
| Chain | Residue |
| A | PHE1203 |
| A | PHE1207 |
| B | MET1209 |
| site_id | BC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PX4 B 1306 |
| Chain | Residue |
| B | PHE1203 |
| B | PHE1207 |
| B | PX41303 |
| D | MET1209 |
| site_id | BC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PX4 C 1301 |
| Chain | Residue |
| C | PRO1075 |
| C | TRP1076 |
| C | PHE1079 |
| C | SER1121 |
| C | ILE1124 |
| site_id | BC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PX4 C 1302 |
| Chain | Residue |
| B | PX41303 |
| C | GLY1026 |
| C | GLY1030 |
| C | SER1034 |
| C | THR1036 |
| D | TYR1142 |
| D | GLY1164 |
| site_id | BC7 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE PX4 C 1303 |
| Chain | Residue |
| A | PX41305 |
| C | MET1137 |
| C | THR1138 |
| C | PHE1141 |
| C | GLY1164 |
| C | GLU1165 |
| C | PHE1167 |
| C | MET1209 |
| D | MET1188 |
| D | TRP1195 |
| D | PHE1203 |
| D | PX41306 |
| site_id | BC8 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE PX4 C 1304 |
| Chain | Residue |
| A | PHE1141 |
| A | THR1162 |
| A | GLY1164 |
| A | GLU1165 |
| A | PHE1167 |
| A | TYR1168 |
| A | MET1209 |
| B | PX41302 |
| C | MET1188 |
| C | PRO1192 |
| C | TRP1195 |
| C | PHE1203 |
| A | MET1137 |
| site_id | BC9 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE PX4 C 1305 |
| Chain | Residue |
| A | ILE1097 |
| A | PHE1107 |
| C | PHE1144 |
| C | MET1147 |
| C | ARG1155 |
| C | TYR1191 |
| C | TYR1193 |
| C | ALA1194 |
| C | VAL1196 |
| site_id | CC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PX4 C 1306 |
| Chain | Residue |
| A | MET1130 |
| A | THR1175 |
| A | MET1209 |
| C | PHE1203 |
| C | PHE1207 |
| site_id | CC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PX4 D 1301 |
| Chain | Residue |
| D | PRO1075 |
| D | TRP1076 |
| D | SER1121 |
| site_id | CC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CA D 1302 |
| Chain | Residue |
| A | HOH1410 |
| B | HOH1408 |
| C | HOH1409 |
| D | HOH1411 |
| site_id | CC4 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CA D 1303 |
| Chain | Residue |
| A | CA1304 |
| site_id | CC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PX4 D 1304 |
| Chain | Residue |
| A | PX41306 |
| B | TYR1142 |
| D | ILE1027 |
| D | GLY1030 |
| D | SER1034 |
| D | THR1036 |
| D | LEU1109 |
| site_id | CC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PX4 D 1305 |
| Chain | Residue |
| C | ILE1097 |
| D | PHE1144 |
| D | PHE1152 |
| D | VAL1190 |
| D | TYR1191 |
| D | TYR1193 |
| D | ALA1194 |
| site_id | CC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PX4 D 1306 |
| Chain | Residue |
| C | PX41303 |
| D | PHE1203 |
| D | THR1206 |
