4MRH

Crystal structure of the murine CD44 hyaluronan binding domain complex with a small molecule

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005540	molecular_function	hyaluronic acid binding
A	0007155	biological_process	cell adhesion
A	0016020	cellular_component	membrane

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE 2CQ A 201

Chain	Residue
A	ARG33
A	PHE60
A	SER136
A	THR138

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site_id	AC2
Number of Residues	9
Details	BINDING SITE FOR RESIDUE DMS A 202

Chain	Residue
A	ARG155
A	ASP156
A	HOH304
A	HOH314
A	CYS32
A	ASN89
A	CYS134
A	THR135
A	SER136

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Functional Information from PROSITE/UniProt

site_id	PS01241
Number of Residues	45
Details	LINK_1 Link domain signature. CqafnstlptmdqmklAlsk.GfetCryGfiegnvvi.PrihpnaiC

Chain	Residue	Details
A	CYS57-CYS101

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	BINDING: BINDING => ECO:0000269|PubMed:17293874

Chain	Residue	Details
A	ARG45
A	ARG82
A	TYR83
A	TYR109

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site_id	SWS_FT_FI2
Number of Residues	5
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255

Chain	Residue	Details
A	ASN29
A	ASN61
A	ASN104
A	ASN115
A	ASN125

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