Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

4MPO

1.90 A resolution structure of CT771 from Chlamydia trachomatis Bound to Hydrolyzed Ap4A Products

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0004081	molecular_function	bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity
A	0006167	biological_process	AMP biosynthetic process
A	0006754	biological_process	ATP biosynthetic process
A	0008796	molecular_function	bis(5'-nucleosyl)-tetraphosphatase activity
A	0016787	molecular_function	hydrolase activity
A	0046872	molecular_function	metal ion binding
B	0000166	molecular_function	nucleotide binding
B	0004081	molecular_function	bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity
B	0006167	biological_process	AMP biosynthetic process
B	0006754	biological_process	ATP biosynthetic process
B	0008796	molecular_function	bis(5'-nucleosyl)-tetraphosphatase activity
B	0016787	molecular_function	hydrolase activity
B	0046872	molecular_function	metal ion binding
C	0000166	molecular_function	nucleotide binding
C	0004081	molecular_function	bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity
C	0006167	biological_process	AMP biosynthetic process
C	0006754	biological_process	ATP biosynthetic process
C	0008796	molecular_function	bis(5'-nucleosyl)-tetraphosphatase activity
C	0016787	molecular_function	hydrolase activity
C	0046872	molecular_function	metal ion binding
D	0000166	molecular_function	nucleotide binding
D	0004081	molecular_function	bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity
D	0006167	biological_process	AMP biosynthetic process
D	0006754	biological_process	ATP biosynthetic process
D	0008796	molecular_function	bis(5'-nucleosyl)-tetraphosphatase activity
D	0016787	molecular_function	hydrolase activity
D	0046872	molecular_function	metal ion binding
E	0000166	molecular_function	nucleotide binding
E	0004081	molecular_function	bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity
E	0006167	biological_process	AMP biosynthetic process
E	0006754	biological_process	ATP biosynthetic process
E	0008796	molecular_function	bis(5'-nucleosyl)-tetraphosphatase activity
E	0016787	molecular_function	hydrolase activity
E	0046872	molecular_function	metal ion binding
F	0000166	molecular_function	nucleotide binding
F	0004081	molecular_function	bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity
F	0006167	biological_process	AMP biosynthetic process
F	0006754	biological_process	ATP biosynthetic process
F	0008796	molecular_function	bis(5'-nucleosyl)-tetraphosphatase activity
F	0016787	molecular_function	hydrolase activity
F	0046872	molecular_function	metal ion binding
G	0000166	molecular_function	nucleotide binding
G	0004081	molecular_function	bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity
G	0006167	biological_process	AMP biosynthetic process
G	0006754	biological_process	ATP biosynthetic process
G	0008796	molecular_function	bis(5'-nucleosyl)-tetraphosphatase activity
G	0016787	molecular_function	hydrolase activity
G	0046872	molecular_function	metal ion binding
H	0000166	molecular_function	nucleotide binding
H	0004081	molecular_function	bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity
H	0006167	biological_process	AMP biosynthetic process
H	0006754	biological_process	ATP biosynthetic process
H	0008796	molecular_function	bis(5'-nucleosyl)-tetraphosphatase activity
H	0016787	molecular_function	hydrolase activity
H	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL A 201

Chain	Residue
A	SER9
A	LYS92
A	HOH349

site_id	AC2
Number of Residues	15
Details	BINDING SITE FOR RESIDUE AMP A 202

Chain	Residue
A	PHE129
A	GLU131
A	HOH307
A	HOH314
A	HOH329
A	HOH330
A	HOH338
A	HOH344
A	HOH351
A	HIS38
A	LYS43
A	TYR80
A	SER81
A	PHE82
A	LYS92

site_id	AC3
Number of Residues	11
Details	BINDING SITE FOR RESIDUE PO4 A 203

Chain	Residue
A	LYS43
A	GLY44
A	HIS45
A	GLU59
A	GLU63
A	GLU111
A	MG204
A	MG205
A	MG206
A	HOH321
A	HOH349

site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG A 204

Chain	Residue
A	GLU59
A	GLU63
A	GLU111
A	PO4203
A	MG205
A	HOH304

site_id	AC5
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MG A 205

Chain	Residue
A	LYS43
A	GLU63
A	GLU111
A	PO4203
A	MG204
A	HOH303
A	HOH349

site_id	AC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG A 206

Chain	Residue
A	GLU59
A	PO4203
A	HOH310
A	HOH315
A	HOH321

site_id	AC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL B 201

Chain	Residue
B	SER9
B	HIS45
B	LYS92
B	HOH338

site_id	AC8
Number of Residues	15
Details	BINDING SITE FOR RESIDUE AMP B 202

Chain	Residue
B	HIS38
B	LYS43
B	TYR80
B	SER81
B	PHE82
B	LYS92
B	PHE129
B	GLU131
B	HOH301
B	HOH308
B	HOH315
B	HOH319
B	HOH321
B	HOH323
B	HOH331

site_id	AC9
Number of Residues	14
Details	BINDING SITE FOR RESIDUE PO4 B 203

Chain	Residue
B	LYS43
B	GLY44
B	HIS45
B	GLU59
B	GLU63
B	GLU111
B	MG204
B	MG205
B	MG206
B	HOH304
B	HOH305
B	HOH318
B	HOH335
B	HOH338

site_id	BC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MG B 204

Chain	Residue
B	GLU59
B	GLU63
B	GLU111
B	PO4203
B	MG205
B	MG206
B	HOH304

site_id	BC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MG B 205

Chain	Residue
B	LYS43
B	GLU63
B	GLU111
B	PO4203
B	MG204
B	HOH307
B	HOH338

site_id	BC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG B 206

Chain	Residue
B	HOH336
B	GLU59
B	PO4203
B	MG204
B	HOH305
B	HOH335

site_id	BC4
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MG C 201

Chain	Residue
C	LYS43
C	GLU63
C	GLU111
C	PO4203
C	MG205
C	HOH304
C	HOH335

site_id	BC5
Number of Residues	8
Details	BINDING SITE FOR RESIDUE MG C 202

Chain	Residue
C	GLU111
C	PO4203
C	MG205
C	MG206
C	HOH306
C	HOH333
C	HOH336
C	HOH337

site_id	BC6
Number of Residues	17
Details	BINDING SITE FOR RESIDUE PO4 C 203

Chain	Residue
C	LYS43
C	GLY44
C	HIS45
C	GLU59
C	GLU63
C	GLU111
C	MG201
C	MG202
C	MG205
C	MG206
C	HOH321
C	HOH333
C	HOH335
C	HOH336
C	HOH337
C	HOH338
C	HOH339

site_id	BC7
Number of Residues	10
Details	BINDING SITE FOR RESIDUE AMP C 204

Chain	Residue
C	HIS38
C	LYS43
C	TYR80
C	SER81
C	PHE82
C	LYS92
C	PHE129
C	GLU131
C	HOH318
C	HOH319

site_id	BC8
Number of Residues	9
Details	BINDING SITE FOR RESIDUE MG C 205

Chain	Residue
C	GLU59
C	GLU63
C	GLU111
C	MG201
C	MG202
C	PO4203
C	MG206
C	HOH324
C	HOH333

site_id	BC9
Number of Residues	8
Details	BINDING SITE FOR RESIDUE MG C 206

Chain	Residue
C	GLU59
C	MG202
C	PO4203
C	MG205
C	HOH308
C	HOH333
C	HOH337
C	HOH338

site_id	CC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL D 201

Chain	Residue
D	SER9
D	HIS45
D	LYS92
D	HOH307

site_id	CC2
Number of Residues	10
Details	BINDING SITE FOR RESIDUE AMP D 202

Chain	Residue
C	ARG91
D	HIS38
D	LYS43
D	TYR80
D	PHE82
D	LYS92
D	PHE129
D	GLU131
D	HOH318
D	HOH330

site_id	CC3
Number of Residues	13
Details	BINDING SITE FOR RESIDUE PO4 D 203

Chain	Residue
D	LYS43
D	GLY44
D	HIS45
D	GLU59
D	GLU63
D	GLU111
D	MG204
D	MG205
D	MG206
D	HOH301
D	HOH304
D	HOH307
D	HOH322

site_id	CC4
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MG D 204

Chain	Residue
D	GLU59
D	GLU63
D	GLU111
D	PO4203
D	MG205
D	MG206
D	HOH304

site_id	CC5
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MG D 205

Chain	Residue
D	LYS43
D	GLU63
D	GLU111
D	PO4203
D	MG204
D	HOH307
D	HOH343

site_id	CC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG D 206

Chain	Residue
D	GLU59
D	PO4203
D	MG204
D	HOH301
D	HOH311
D	HOH322

site_id	CC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG E 201

Chain	Residue
B	GLY36
B	HOH301
E	ASP114
E	VAL115
E	HOH336
E	HOH348

site_id	CC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL E 202

Chain	Residue
E	SER9
E	HIS45
E	LYS92
E	HOH307

site_id	CC9
Number of Residues	14
Details	BINDING SITE FOR RESIDUE PO4 E 203

Chain	Residue
E	LYS43
E	GLY44
E	HIS45
E	GLU59
E	GLU63
E	GLU111
E	MG205
E	MG206
E	MG207
E	HOH303
E	HOH308
E	HOH320
E	HOH333
E	HOH338

site_id	DC1
Number of Residues	13
Details	BINDING SITE FOR RESIDUE AMP E 204

Chain	Residue
E	HIS38
E	LYS43
E	TYR80
E	SER81
E	PHE82
E	LYS92
E	PHE129
E	GLU131
E	HOH313
E	HOH314
E	HOH316
E	HOH319
E	HOH344

site_id	DC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MG E 205

Chain	Residue
E	GLU59
E	GLU63
E	GLU111
E	PO4203
E	MG206
E	MG207
E	HOH303

site_id	DC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MG E 206

Chain	Residue
E	LYS43
E	GLU63
E	GLU111
E	PO4203
E	MG205
E	HOH305
E	HOH307

site_id	DC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG E 207

Chain	Residue
E	GLU59
E	PO4203
E	MG205
E	HOH301
E	HOH308
E	HOH337

site_id	DC5
Number of Residues	11
Details	BINDING SITE FOR RESIDUE AMP F 201

Chain	Residue
F	HIS38
F	LYS43
F	TYR80
F	SER81
F	PHE82
F	LYS92
F	PHE129
F	GLU131
F	HOH310
F	HOH315
F	HOH333

site_id	DC6
Number of Residues	12
Details	BINDING SITE FOR RESIDUE PO4 F 202

Chain	Residue
F	LYS43
F	GLY44
F	HIS45
F	GLU59
F	GLU63
F	GLU111
F	MG203
F	MG204
F	MG205
F	HOH309
F	HOH327
F	HOH329

site_id	DC7
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MG F 203

Chain	Residue
F	GLU59
F	GLU63
F	GLU111
F	PO4202
F	MG204
F	MG205
F	HOH325

site_id	DC8
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MG F 204

Chain	Residue
F	LYS43
F	GLU63
F	GLU111
F	PO4202
F	MG203
F	HOH303
F	HOH309

site_id	DC9
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG F 205

Chain	Residue
F	GLU59
F	PO4202
F	MG203
F	HOH302
F	HOH327
F	HOH329

site_id	EC1
Number of Residues	10
Details	BINDING SITE FOR RESIDUE AMP G 201

Chain	Residue
G	HIS38
G	LYS43
G	TYR80
G	SER81
G	PHE82
G	LYS92
G	PHE129
G	GLU131
G	HOH301
G	HOH304

site_id	EC2
Number of Residues	9
Details	BINDING SITE FOR RESIDUE PO4 G 202

Chain	Residue
G	LYS43
G	GLY44
G	HIS45
G	GLU59
G	GLU63
G	GLU111
G	MG203
G	MG204
G	MG205

site_id	EC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG G 203

Chain	Residue
G	GLU59
G	GLU63
G	GLU111
G	PO4202
G	MG204

site_id	EC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG G 204

Chain	Residue
G	LYS43
G	GLU63
G	GLU111
G	PO4202
G	MG203

site_id	EC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG G 205

Chain	Residue
G	GLU59
G	PO4202

site_id	EC6
Number of Residues	12
Details	BINDING SITE FOR RESIDUE AMP H 201

Chain	Residue
H	HIS38
H	LYS43
H	TYR80
H	SER81
H	PHE82
H	LYS92
H	PHE129
H	GLU131
H	HOH317
H	HOH319
H	HOH325
H	HOH331

site_id	EC7
Number of Residues	11
Details	BINDING SITE FOR RESIDUE PO4 H 202

Chain	Residue
H	LYS43
H	GLY44
H	HIS45
H	GLU59
H	GLU63
H	GLU111
H	MG203
H	MG204
H	MG205
H	HOH306
H	HOH310

site_id	EC8
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MG H 203

Chain	Residue
H	GLU59
H	GLU63
H	GLU111
H	PO4202
H	MG204
H	MG205
H	HOH306

site_id	EC9
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MG H 204

Chain	Residue
H	LYS43
H	GLU63
H	GLU111
H	PO4202
H	MG203
H	HOH304
H	HOH310

site_id	FC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG H 205

Chain	Residue
H	GLU59
H	PO4202
H	MG203
H	HOH305
H	HOH307
H	HOH309

site_id	FC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG H 206

Chain	Residue
A	GLY36
A	HOH338
H	ASP114
H	VAL115
H	HOH302
H	HOH346

site_id	FC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL H 207

Chain	Residue
H	SER9
H	HIS45
H	LYS92
H	HOH310

Functional Information from PROSITE/UniProt

site_id	PS00893
Number of Residues	22
Details	NUDIX_BOX Nudix box signature. GhaeekEgpqeAAeRELvEEtG

Chain	Residue	Details
A	GLY44-GLY65

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)