4MPM
Wild-type human neuroglobin
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0001666 | biological_process | response to hypoxia |
| A | 0005092 | molecular_function | GDP-dissociation inhibitor activity |
| A | 0005344 | molecular_function | oxygen carrier activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005739 | cellular_component | mitochondrion |
| A | 0005759 | cellular_component | mitochondrial matrix |
| A | 0005829 | cellular_component | cytosol |
| A | 0015671 | biological_process | oxygen transport |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0019825 | molecular_function | oxygen binding |
| A | 0020037 | molecular_function | heme binding |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0071456 | biological_process | cellular response to hypoxia |
| A | 0098809 | molecular_function | nitrite reductase activity |
| B | 0001666 | biological_process | response to hypoxia |
| B | 0005092 | molecular_function | GDP-dissociation inhibitor activity |
| B | 0005344 | molecular_function | oxygen carrier activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005739 | cellular_component | mitochondrion |
| B | 0005759 | cellular_component | mitochondrial matrix |
| B | 0005829 | cellular_component | cytosol |
| B | 0015671 | biological_process | oxygen transport |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0019825 | molecular_function | oxygen binding |
| B | 0020037 | molecular_function | heme binding |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0071456 | biological_process | cellular response to hypoxia |
| B | 0098809 | molecular_function | nitrite reductase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE HEM A 201 |
| Chain | Residue |
| A | PHE42 |
| A | HIS96 |
| A | VAL99 |
| A | VAL101 |
| A | PHE106 |
| A | VAL109 |
| A | HOH319 |
| A | HOH381 |
| A | HOH394 |
| B | LEU70 |
| B | HOH357 |
| A | ASN45 |
| B | HOH372 |
| A | GLU60 |
| A | HIS64 |
| A | LYS67 |
| A | VAL68 |
| A | VAL71 |
| A | LEU92 |
| A | LYS95 |
| site_id | AC2 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE HEM B 201 |
| Chain | Residue |
| A | THR77 |
| A | ASN78 |
| A | HOH301 |
| B | LEU38 |
| B | LEU41 |
| B | PHE42 |
| B | HIS64 |
| B | LYS67 |
| B | VAL68 |
| B | VAL71 |
| B | LEU92 |
| B | HIS96 |
| B | VAL109 |
| B | HOH301 |
| B | HOH328 |
| B | HOH389 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | BINDING: distal binding residue; reversible => ECO:0000255|PROSITE-ProRule:PRU00238, ECO:0000269|PubMed:12962627, ECO:0000269|PubMed:24699645, ECO:0007744|PDB:1OJ6, ECO:0007744|PDB:4MPM |
| Chain | Residue | Details |
| A | HIS64 | |
| B | HIS64 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | BINDING: proximal binding residue => ECO:0000269|PubMed:12962627, ECO:0000269|PubMed:24699645, ECO:0007744|PDB:1OJ6, ECO:0007744|PDB:4MPM |
| Chain | Residue | Details |
| A | HIS96 | |
| B | HIS96 |
