4MOB
Acyl-Coenzyme A thioesterase 12 in complex with ADP
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0016790 | molecular_function | thiolester hydrolase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE COA A 401 |
| Chain | Residue |
| A | VAL52 |
| A | ARG144 |
| A | THR200 |
| A | LYS234 |
| A | PHE235 |
| A | ARG236 |
| A | GLY237 |
| A | PRO238 |
| A | HOH585 |
| A | THR53 |
| A | ALA54 |
| A | SER55 |
| A | PHE81 |
| A | SER82 |
| A | THR83 |
| A | SER84 |
| A | THR110 |
| site_id | AC2 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE ADP A 402 |
| Chain | Residue |
| A | THR248 |
| A | ALA249 |
| A | ILE250 |
| A | ASN252 |
| A | GLY262 |
| A | VAL263 |
| A | ARG264 |
| A | SER283 |
| A | PHE285 |
| A | ARG312 |
| A | ARG313 |
| A | HOH567 |
| A | HOH572 |
| A | HOH577 |
| A | HOH578 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 115 |
| Details | Domain: {"description":"HotDog ACOT-type 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU01106","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | Binding site: {} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"NOV-2007","submissionDatabase":"PDB data bank","title":"Human acyl-coenzyme A thioesterase 12.","authoringGroup":["Structural genomics consortium (SGC)"]}}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 3 |
| Details | Modified residue: {"description":"N6-succinyllysine","evidences":[{"source":"UniProtKB","id":"Q9DBK0","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
