4MN9

Fifteen minutes iron loaded frog M ferritin mutant H54Q

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004322	molecular_function	ferroxidase activity
A	0005737	cellular_component	cytoplasm
A	0006826	biological_process	iron ion transport
A	0006879	biological_process	intracellular iron ion homeostasis
A	0008198	molecular_function	ferrous iron binding
A	0008199	molecular_function	ferric iron binding
A	0016491	molecular_function	oxidoreductase activity
A	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE FE A 201

Chain	Residue
A	GLU23
A	GLU58
A	HIS61
A	HOH373
A	HOH418

---

site_id	AC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE FE A 202

Chain	Residue
A	HOH418
A	HOH622
A	HOH623
A	GLU58
A	GLU103
A	GLN137
A	FE203

---

site_id	AC3
Number of Residues	8
Details	BINDING SITE FOR RESIDUE FE A 203

Chain	Residue
A	GLN54
A	GLU103
A	ASP140
A	FE202
A	FE204
A	HOH622
A	HOH623
A	HOH625

---

site_id	AC4
Number of Residues	9
Details	BINDING SITE FOR RESIDUE FE A 204

Chain	Residue
A	GLU57
A	GLU136
A	ASP140
A	ARG143
A	FE203
A	HOH625
A	HOH626
A	HOH627
A	HOH628

---

site_id	AC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE FE A 205

Chain	Residue
A	GLU53
A	GLU57
A	HOH546
A	HOH628
A	HOH629
A	HOH653

---

site_id	AC6
Number of Residues	12
Details	BINDING SITE FOR RESIDUE FE A 206

Chain	Residue
A	HIS169
A	HIS169
A	HIS169
A	HIS169
A	CL224
A	CL224
A	CL224
A	CL224
A	HOH412
A	HOH412
A	HOH412
A	HOH412

---

site_id	AC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG A 207

Chain	Residue
A	HOH331
A	HOH331
A	HOH331
A	HOH368
A	HOH368
A	HOH368

---

site_id	AC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG A 208

Chain	Residue
A	HOH509
A	HOH509
A	HOH509
A	HOH532
A	HOH532
A	HOH532

---

site_id	AC9
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG A 209

Chain	Residue
A	HOH393
A	HOH396
A	HOH419
A	HOH448
A	HOH453
A	HOH455

---

site_id	BC1
Number of Residues	8
Details	BINDING SITE FOR RESIDUE MG A 210

Chain	Residue
A	HOH322
A	HOH322
A	HOH345
A	HOH345
A	HOH370
A	HOH370
A	HOH374
A	HOH374

---

site_id	BC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG A 211

Chain	Residue
A	SER10
A	HOH334
A	HOH385
A	HOH413
A	HOH426
A	HOH470

---

site_id	BC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MG A 212

Chain	Residue
A	HIS45
A	HOH478
A	HOH514
A	HOH610
A	HOH611
A	HOH618
A	HOH619

---

site_id	BC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG A 213

Chain	Residue
A	HOH375
A	HOH512
A	HOH550
A	HOH613
A	HOH630
A	HOH631

---

site_id	BC5
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MG A 214

Chain	Residue
A	HOH344
A	HOH565
A	HOH566
A	HOH604
A	HOH632
A	HOH648
A	HOH652

---

site_id	BC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL A 215

Chain	Residue
A	ARG5
A	ASN7
A	TYR8
A	HOH544

---

site_id	BC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL A 216

Chain	Residue
A	ASN17
A	HOH369

---

site_id	BC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL A 217

Chain	Residue
A	ASP87
A	GLU88

---

site_id	BC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CL A 218

Chain	Residue
A	SER131
A	GLU132
A	TYR133
A	GLU135
A	GLU136

---

site_id	CC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL A 219

Chain	Residue
A	LYS67
A	LYS71
A	HOH401

---

site_id	CC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CL A 220

Chain	Residue
A	GLN101
A	LEU102
A	THR105
A	HOH319
A	HOH463

---

site_id	CC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL A 221

Chain	Residue
A	GLU85
A	ARG86
A	HOH381
A	HOH390

---

site_id	CC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL A 222

Chain	Residue
A	ASP112
A	HOH318

---

site_id	CC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL A 223

Chain	Residue
A	ASN150
A	HOH364

---

site_id	CC6
Number of Residues	12
Details	BINDING SITE FOR RESIDUE CL A 224

Chain	Residue
A	LEU165
A	LEU165
A	LEU165
A	LEU165
A	HIS169
A	HIS169
A	HIS169
A	HIS169
A	FE206
A	FE206
A	FE206
A	FE206

---

Functional Information from PROSITE/UniProt

site_id	PS00204
Number of Residues	21
Details	FERRITIN_2 Ferritin iron-binding regions signature 2. DphLCDFLEseYLeeqvkdIK

Chain	Residue	Details
A	ASP122-LYS142

---

site_id	PS00540
Number of Residues	19
Details	FERRITIN_1 Ferritin iron-binding regions signature 1. EeREhaEKFMkyQNkRgGR

Chain	Residue	Details
A	GLU57-ARG75

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	149
Details	Domain: {"description":"Ferritin-like diiron","evidences":[{"source":"PROSITE-ProRule","id":"PRU00085","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	6
Details	Binding site: {}

Chain

Residue

Details

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