4MMG
crystal structure of YafQ mutant H87Q from E.coli
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004521 | molecular_function | RNA endonuclease activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0006402 | biological_process | mRNA catabolic process |
| A | 0006415 | biological_process | translational termination |
| A | 0016892 | molecular_function | RNA endonuclease activity producing 3'-phosphomonoesters, hydrolytic mechanism |
| A | 0040008 | biological_process | regulation of growth |
| A | 0043022 | molecular_function | ribosome binding |
| A | 0044010 | biological_process | single-species biofilm formation |
| A | 0045892 | biological_process | negative regulation of DNA-templated transcription |
| A | 0046677 | biological_process | response to antibiotic |
| A | 0110001 | cellular_component | toxin-antitoxin complex |
| B | 0004521 | molecular_function | RNA endonuclease activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0006402 | biological_process | mRNA catabolic process |
| B | 0006415 | biological_process | translational termination |
| B | 0016892 | molecular_function | RNA endonuclease activity producing 3'-phosphomonoesters, hydrolytic mechanism |
| B | 0040008 | biological_process | regulation of growth |
| B | 0043022 | molecular_function | ribosome binding |
| B | 0044010 | biological_process | single-species biofilm formation |
| B | 0045892 | biological_process | negative regulation of DNA-templated transcription |
| B | 0046677 | biological_process | response to antibiotic |
| B | 0110001 | cellular_component | toxin-antitoxin complex |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 A 101 |
| Chain | Residue |
| A | HIS50 |
| A | HIS63 |
| A | GLN87 |
| A | HOH221 |
| A | HOH291 |
| A | HOH385 |
| B | HIS23 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE SO4 A 102 |
| Chain | Residue |
| A | HOH202 |
| A | HOH236 |
| A | HOH245 |
| A | HOH283 |
| A | HOH309 |
| A | HOH335 |
| A | HOH376 |
| B | HOH251 |
| A | ARG22 |
| A | ALA89 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 103 |
| Chain | Residue |
| A | ARG80 |
| A | GLU82 |
| A | HOH215 |
| A | HOH217 |
| A | HOH314 |
| A | HOH375 |
| site_id | AC4 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE SO4 B 101 |
| Chain | Residue |
| A | HIS23 |
| B | HIS50 |
| B | HIS63 |
| B | HOH216 |
| B | HOH253 |
| B | HOH307 |
| B | HOH365 |
| B | HOH389 |
| B | HOH426 |
| B | HOH437 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 102 |
| Chain | Residue |
| B | ARG80 |
| B | GLU82 |
| B | HOH233 |
| B | HOH249 |
| site_id | AC6 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO4 B 103 |
| Chain | Residue |
| A | HOH318 |
| B | ARG22 |
| B | ALA89 |
| B | HOH206 |
| B | HOH290 |
| B | HOH312 |
| B | HOH316 |
| B | HOH321 |
| B | HOH420 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton donor","evidences":[{"evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
