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4MMG

crystal structure of YafQ mutant H87Q from E.coli

Functional Information from GO Data
ChainGOidnamespacecontents
A0003677molecular_functionDNA binding
A0003723molecular_functionRNA binding
A0004519molecular_functionendonuclease activity
A0004521molecular_functionRNA endonuclease activity
A0005515molecular_functionprotein binding
A0006402biological_processmRNA catabolic process
A0006415biological_processtranslational termination
A0016892molecular_functionRNA endonuclease activity, producing 3'-phosphomonoesters
A0040008biological_processregulation of growth
A0043022molecular_functionribosome binding
A0044010biological_processsingle-species biofilm formation
A0045892biological_processnegative regulation of DNA-templated transcription
A0046677biological_processresponse to antibiotic
A0110001cellular_componenttoxin-antitoxin complex
B0003677molecular_functionDNA binding
B0003723molecular_functionRNA binding
B0004519molecular_functionendonuclease activity
B0004521molecular_functionRNA endonuclease activity
B0005515molecular_functionprotein binding
B0006402biological_processmRNA catabolic process
B0006415biological_processtranslational termination
B0016892molecular_functionRNA endonuclease activity, producing 3'-phosphomonoesters
B0040008biological_processregulation of growth
B0043022molecular_functionribosome binding
B0044010biological_processsingle-species biofilm formation
B0045892biological_processnegative regulation of DNA-templated transcription
B0046677biological_processresponse to antibiotic
B0110001cellular_componenttoxin-antitoxin complex
Functional Information from PDB Data
site_idAC1
Number of Residues7
DetailsBINDING SITE FOR RESIDUE SO4 A 101
ChainResidue
AHIS50
AHIS63
AGLN87
AHOH221
AHOH291
AHOH385
BHIS23

site_idAC2
Number of Residues10
DetailsBINDING SITE FOR RESIDUE SO4 A 102
ChainResidue
AHOH202
AHOH236
AHOH245
AHOH283
AHOH309
AHOH335
AHOH376
BHOH251
AARG22
AALA89

site_idAC3
Number of Residues6
DetailsBINDING SITE FOR RESIDUE SO4 A 103
ChainResidue
AARG80
AGLU82
AHOH215
AHOH217
AHOH314
AHOH375

site_idAC4
Number of Residues10
DetailsBINDING SITE FOR RESIDUE SO4 B 101
ChainResidue
AHIS23
BHIS50
BHIS63
BHOH216
BHOH253
BHOH307
BHOH365
BHOH389
BHOH426
BHOH437

site_idAC5
Number of Residues4
DetailsBINDING SITE FOR RESIDUE SO4 B 102
ChainResidue
BARG80
BGLU82
BHOH233
BHOH249

site_idAC6
Number of Residues9
DetailsBINDING SITE FOR RESIDUE SO4 B 103
ChainResidue
AHOH318
BARG22
BALA89
BHOH206
BHOH290
BHOH312
BHOH316
BHOH321
BHOH420

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsACT_SITE: Proton donor => ECO:0000305
ChainResidueDetails
AGLN87
BGLN87

226707

PDB entries from 2024-10-30

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