4ML5

one minute iron loaded frog M ferritin mutant H54Q

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004322	molecular_function	ferroxidase activity
A	0005737	cellular_component	cytoplasm
A	0006826	biological_process	iron ion transport
A	0006879	biological_process	intracellular iron ion homeostasis
A	0008198	molecular_function	ferrous iron binding
A	0008199	molecular_function	ferric iron binding
A	0016491	molecular_function	oxidoreductase activity
A	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE FE2 A 201

Chain	Residue
A	GLU23
A	GLU58
A	HIS61
A	HOH663
A	HOH673

---

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE FE2 A 202

Chain	Residue
A	HOH484
A	HOH669
A	GLU57
A	GLU136
A	ASP140
A	ARG143

---

site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE FE2 A 203

Chain	Residue
A	GLU53
A	GLU57
A	HOH437
A	HOH484
A	HOH489
A	HOH546

---

site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE FE2 A 204

Chain	Residue
A	GLN54
A	GLU103
A	ASP140
A	HOH589
A	HOH649
A	HOH669

---

site_id	AC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG A 205

Chain	Residue
A	SER10
A	HOH362
A	HOH441
A	HOH529
A	HOH530
A	HOH591

---

site_id	AC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG A 206

Chain	Residue
A	HOH312
A	HOH312
A	HOH312
A	HOH337
A	HOH337
A	HOH337

---

site_id	AC7
Number of Residues	9
Details	BINDING SITE FOR RESIDUE MG A 207

Chain	Residue
A	ASP127
A	ASP127
A	ASP127
A	HOH378
A	HOH378
A	HOH378
A	HOH674
A	HOH674
A	HOH674

---

site_id	AC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG A 208

Chain	Residue
A	HOH471
A	HOH475
A	HOH590
A	HOH593
A	HOH664
A	HOH676

---

site_id	AC9
Number of Residues	8
Details	BINDING SITE FOR RESIDUE MG A 209

Chain	Residue
A	HOH396
A	HOH396
A	HOH456
A	HOH456
A	HOH680
A	HOH680
A	HOH681
A	HOH681

---

site_id	BC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG A 210

Chain	Residue
A	HOH399
A	HOH438
A	HOH460
A	HOH644
A	HOH665
A	HOH679

---

site_id	BC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG A 211

Chain	Residue
A	HOH365
A	HOH447
A	HOH533
A	HOH555
A	HOH561
A	HOH601

---

site_id	BC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG A 212

Chain	Residue
A	HOH490
A	HOH567
A	HOH578
A	HOH587

---

site_id	BC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG A 213

Chain	Residue
A	HOH348
A	HOH429
A	HOH553
A	HOH600
A	HOH623
A	HOH650

---

site_id	BC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CL A 214

Chain	Residue
A	SER131
A	GLU132
A	TYR133
A	GLU135
A	GLU136

---

site_id	BC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL A 215

Chain	Residue
A	ASP87
A	GLU88
A	HOH519

---

site_id	BC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL A 216

Chain	Residue
A	LYS82
A	LYS82
A	HOH307
A	HOH394

---

site_id	BC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CL A 217

Chain	Residue
A	ASN7
A	GLN108
A	LYS115
A	HOH371
A	HOH418

---

site_id	BC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL A 218

Chain	Residue
A	HOH436
A	HOH373
A	HOH402

---

site_id	CC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL A 219

Chain	Residue
A	GLN101
A	LEU102
A	THR105
A	HOH500

---

site_id	CC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL A 220

Chain	Residue
A	HIS169
A	HIS169
A	HIS169
A	HIS169

---

site_id	CC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL A 221

Chain	Residue
A	HIS169
A	HIS169
A	HIS169
A	HIS169

---

site_id	CC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL A 222

Chain	Residue
A	ARG5
A	ASN7
A	TYR8
A	HOH543

---

site_id	CC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL A 223

Chain	Residue
A	ASN17
A	HOH361

---

site_id	CC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL A 224

Chain	Residue
A	SER10
A	HOH544
A	HOH682

---

site_id	CC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CL A 225

Chain	Residue
A	ASN150
A	LYS168
A	SER170
A	CL226
A	HOH313

---

site_id	CC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CL A 226

Chain	Residue
A	ASP146
A	PHE147
A	ASN150
A	CL225
A	HOH331
A	HOH403

---

site_id	CC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL A 227

Chain	Residue
A	GLY155
A	ASN159
A	HOH656

---

site_id	DC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL A 228

Chain	Residue
A	HOH570

---

site_id	DC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL A 229

Chain	Residue
A	LYS67
A	LYS71
A	LYS139
A	HOH381

---

Functional Information from PROSITE/UniProt

site_id	PS00204
Number of Residues	21
Details	FERRITIN_2 Ferritin iron-binding regions signature 2. DphLCDFLEseYLeeqvkdIK

Chain	Residue	Details
A	ASP122-LYS142

---

site_id	PS00540
Number of Residues	19
Details	FERRITIN_1 Ferritin iron-binding regions signature 1. EeREhaEKFMkyQNkRgGR

Chain	Residue	Details
A	GLU57-ARG75

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	149
Details	Domain: {"description":"Ferritin-like diiron","evidences":[{"source":"PROSITE-ProRule","id":"PRU00085","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	6
Details	Binding site: {}

Chain

Residue

Details

---