4MKK

Crystal structure of C115A mutant L-methionine gamma-lyase from Citrobacter freundii modified by allicine

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000096	biological_process	sulfur amino acid metabolic process
A	0003824	molecular_function	catalytic activity
A	0005737	cellular_component	cytoplasm
A	0016829	molecular_function	lyase activity
A	0016846	molecular_function	carbon-sulfur lyase activity
A	0018826	molecular_function	methionine gamma-lyase activity
A	0019346	biological_process	transsulfuration
A	0030170	molecular_function	pyridoxal phosphate binding
A	0047982	molecular_function	homocysteine desulfhydrase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	BINDING SITE FOR RESIDUE PGE A 401

Chain	Residue
A	PRO191
A	TYR192
A	CYS193
A	GLN195
A	GLN303
A	SER307
A	HOH751
A	HOH827

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site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE PGE A 402

Chain	Residue
A	LYS274
A	PRO382
A	GLU383
A	GLU270

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site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE NA A 403

Chain	Residue
A	SER35
A	THR36
A	THR209
A	SER339
A	ASP342

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site_id	AC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE NA A 404

Chain	Residue
A	ALA84
A	C1S245
A	MET246

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site_id	AC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE NA A 405

Chain	Residue
A	ILE317
A	GLY319
A	GLY320
A	HOH582
A	HOH627

---

site_id	AC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL A 406

Chain	Residue
A	ARG267
A	LEU379
A	GLU380
A	NA407

---

site_id	AC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE NA A 407

Chain	Residue
A	PRO382
A	CL406
A	HOH537
A	HOH598
A	HOH672

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site_id	AC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE NA A 408

Chain	Residue
A	PRO64
A	ASP67
A	HOH759

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site_id	AC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE K A 409

Chain	Residue
A	TYR113
A	VAL338

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