4MJY

Sixty minutes iron loaded frog M ferritin mutant H54Q

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004322	molecular_function	ferroxidase activity
A	0005737	cellular_component	cytoplasm
A	0006826	biological_process	iron ion transport
A	0006879	biological_process	intracellular iron ion homeostasis
A	0008198	molecular_function	ferrous iron binding
A	0008199	molecular_function	ferric iron binding
A	0016491	molecular_function	oxidoreductase activity
A	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE FE2 A 201

Chain	Residue
A	GLU23
A	GLU58
A	HIS61
A	FE2202
A	HOH383
A	HOH480

---

site_id	AC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE FE2 A 202

Chain	Residue
A	FE2201
A	HOH480
A	HOH619
A	HOH620
A	GLU58
A	GLU103
A	GLN137

---

site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE FE2 A 203

Chain	Residue
A	GLN54
A	GLU57
A	GLU136
A	ASP140
A	FE2208
A	HOH620

---

site_id	AC4
Number of Residues	12
Details	BINDING SITE FOR RESIDUE FE2 A 204

Chain	Residue
A	HIS169
A	HIS169
A	HIS169
A	HIS169
A	CL213
A	CL213
A	CL213
A	CL213
A	HOH377
A	HOH377
A	HOH377
A	HOH377

---

site_id	AC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE FE2 A 205

Chain	Residue
A	HOH468
A	HOH468
A	HOH468
A	HOH470
A	HOH470
A	HOH470

---

site_id	AC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE FE2 A 206

Chain	Residue
A	HOH329
A	HOH329
A	HOH329
A	HOH342
A	HOH342
A	HOH342

---

site_id	AC7
Number of Residues	8
Details	BINDING SITE FOR RESIDUE FE2 A 207

Chain	Residue
A	HOH345
A	HOH345
A	HOH348
A	HOH348
A	HOH621
A	HOH621
A	HOH622
A	HOH622

---

site_id	AC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE FE2 A 208

Chain	Residue
A	GLU57
A	GLU136
A	FE2203
A	HOH610

---

site_id	AC9
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG A 209

Chain	Residue
A	SER10
A	HOH344
A	HOH424
A	HOH482
A	HOH492
A	HOH547

---

site_id	BC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG A 210

Chain	Residue
A	HOH352
A	HOH554
A	HOH576
A	HOH595
A	HOH624
A	HOH625

---

site_id	BC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG A 211

Chain	Residue
A	HOH488
A	HOH555
A	HOH597
A	HOH635
A	HOH636
A	HOH637

---

site_id	BC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL A 212

Chain	Residue
A	ARG5
A	ASN7
A	TYR8

---

site_id	BC4
Number of Residues	12
Details	BINDING SITE FOR RESIDUE CL A 213

Chain	Residue
A	LEU165
A	LEU165
A	LEU165
A	LEU165
A	HIS169
A	HIS169
A	HIS169
A	HIS169
A	FE2204
A	FE2204
A	FE2204
A	FE2204

---

site_id	BC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL A 214

Chain	Residue
A	ASN150
A	SER170
A	HOH350

---

site_id	BC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL A 215

Chain	Residue
A	LYS82
A	LYS82
A	HOH309
A	HOH379

---

site_id	BC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL A 216

Chain	Residue
A	ARG39

---

Functional Information from PROSITE/UniProt

site_id	PS00204
Number of Residues	21
Details	FERRITIN_2 Ferritin iron-binding regions signature 2. DphLCDFLEseYLeeqvkdIK

Chain	Residue	Details
A	ASP122-LYS142

---

site_id	PS00540
Number of Residues	19
Details	FERRITIN_1 Ferritin iron-binding regions signature 1. EeREhaEKFMkyQNkRgGR

Chain	Residue	Details
A	GLU57-ARG75

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	149
Details	Domain: {"description":"Ferritin-like diiron","evidences":[{"source":"PROSITE-ProRule","id":"PRU00085","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	6
Details	Binding site: {}

Chain

Residue

Details

---