4MIN
Crystal Structure of myo-inositol dehydrogenase from Lactobacillus casei with bound cofactor NAD
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0019310 | biological_process | inositol catabolic process |
| A | 0050112 | molecular_function | inositol 2-dehydrogenase (NAD+) activity |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0019310 | biological_process | inositol catabolic process |
| B | 0050112 | molecular_function | inositol 2-dehydrogenase (NAD+) activity |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0016491 | molecular_function | oxidoreductase activity |
| C | 0019310 | biological_process | inositol catabolic process |
| C | 0050112 | molecular_function | inositol 2-dehydrogenase (NAD+) activity |
| D | 0000166 | molecular_function | nucleotide binding |
| D | 0016491 | molecular_function | oxidoreductase activity |
| D | 0019310 | biological_process | inositol catabolic process |
| D | 0050112 | molecular_function | inositol 2-dehydrogenase (NAD+) activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE NAD A 401 |
| Chain | Residue |
| A | GLY11 |
| A | HIS79 |
| A | GLU96 |
| A | LYS97 |
| A | GLY124 |
| A | HIS176 |
| A | TYR282 |
| A | HOH542 |
| A | HOH688 |
| A | ALA12 |
| A | MET13 |
| A | ASP35 |
| A | ILE36 |
| A | VAL73 |
| A | SER74 |
| A | PHE75 |
| A | ALA78 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL A 402 |
| Chain | Residue |
| A | GLN266 |
| B | GLN266 |
| B | THR268 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 403 |
| Chain | Residue |
| A | ARG152 |
| A | ALA153 |
| A | SER154 |
| A | GLU241 |
| A | HOH553 |
| C | ARG152 |
| C | GLU241 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 404 |
| Chain | Residue |
| A | THR26 |
| A | GLY27 |
| A | HOH666 |
| A | HOH682 |
| D | THR26 |
| D | GLY27 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 405 |
| Chain | Residue |
| B | ARG198 |
| B | HOH767 |
| D | PRO148 |
| D | LYS220 |
| D | HOH643 |
| D | HOH767 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 A 406 |
| Chain | Residue |
| A | ARG198 |
| A | HOH532 |
| A | HOH620 |
| A | HOH701 |
| C | ALA147 |
| C | PRO148 |
| C | LYS220 |
| site_id | AC7 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE NAD B 401 |
| Chain | Residue |
| B | GLY9 |
| B | GLY11 |
| B | ALA12 |
| B | MET13 |
| B | ASP35 |
| B | ILE36 |
| B | VAL73 |
| B | SER74 |
| B | PHE75 |
| B | ALA78 |
| B | HIS79 |
| B | GLU96 |
| B | LYS97 |
| B | GLY124 |
| B | MET126 |
| B | TYR282 |
| B | HOH527 |
| B | HOH607 |
| B | HOH614 |
| B | HOH616 |
| B | HOH625 |
| B | HOH638 |
| B | HOH645 |
| B | HOH716 |
| site_id | AC8 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL B 402 |
| Chain | Residue |
| A | HOH515 |
| B | LEU140 |
| B | ASP141 |
| B | GLY143 |
| B | GLY146 |
| B | PRO148 |
| B | HOH611 |
| B | HOH766 |
| site_id | AC9 |
| Number of Residues | 26 |
| Details | BINDING SITE FOR RESIDUE NAD C 401 |
| Chain | Residue |
| C | HOH654 |
| C | HOH731 |
| C | HOH753 |
| C | HOH765 |
| C | HOH767 |
| B | HOH738 |
| B | HOH741 |
| C | GLY11 |
| C | ALA12 |
| C | MET13 |
| C | ASP35 |
| C | ILE36 |
| C | VAL73 |
| C | SER74 |
| C | PHE75 |
| C | ALA78 |
| C | HIS79 |
| C | GLU96 |
| C | LYS97 |
| C | GLY124 |
| C | HIS176 |
| C | TYR282 |
| C | HOH585 |
| C | HOH601 |
| C | HOH627 |
| C | HOH643 |
| site_id | BC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL C 402 |
| Chain | Residue |
| A | ARG152 |
| A | GLU241 |
| C | ARG152 |
| C | ALA153 |
| C | SER154 |
| C | GLU241 |
| C | HOH619 |
| site_id | BC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 C 403 |
| Chain | Residue |
| A | PRO148 |
| A | LYS220 |
| C | ARG198 |
| C | HOH573 |
| site_id | BC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 C 404 |
| Chain | Residue |
| B | LEU25 |
| B | THR26 |
| B | GLY27 |
| C | THR26 |
| C | GLY27 |
| C | HOH760 |
| site_id | BC4 |
| Number of Residues | 29 |
| Details | BINDING SITE FOR RESIDUE NAD D 401 |
| Chain | Residue |
| C | HOH606 |
| D | GLY11 |
| D | ALA12 |
| D | MET13 |
| D | ASP35 |
| D | ILE36 |
| D | VAL73 |
| D | SER74 |
| D | ALA78 |
| D | HIS79 |
| D | GLU96 |
| D | LYS97 |
| D | MET126 |
| D | ASP172 |
| D | HIS176 |
| D | TRP274 |
| D | TYR282 |
| D | HOH501 |
| D | HOH536 |
| D | HOH587 |
| D | HOH595 |
| D | HOH597 |
| D | HOH664 |
| D | HOH666 |
| D | HOH682 |
| D | HOH761 |
| D | HOH762 |
| D | HOH770 |
| D | HOH783 |
| site_id | BC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL D 402 |
| Chain | Residue |
| D | TYR129 |
| D | ARG134 |
| D | GLU288 |
| D | SO4403 |
| D | HOH755 |
| site_id | BC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 D 403 |
| Chain | Residue |
| D | ARG134 |
| D | TRP183 |
| D | GOL402 |
