4MHE

Crystal structure of CC-chemokine 18

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005125	molecular_function	cytokine activity
A	0005515	molecular_function	protein binding
A	0005576	cellular_component	extracellular region
A	0005615	cellular_component	extracellular space
A	0006935	biological_process	chemotaxis
A	0006954	biological_process	inflammatory response
A	0006955	biological_process	immune response
A	0007154	biological_process	cell communication
A	0007165	biological_process	signal transduction
A	0007267	biological_process	cell-cell signaling
A	0008009	molecular_function	chemokine activity
A	0030335	biological_process	positive regulation of cell migration
A	0048020	molecular_function	CCR chemokine receptor binding
A	0060326	biological_process	cell chemotaxis
A	0061844	biological_process	antimicrobial humoral immune response mediated by antimicrobial peptide
A	0070098	biological_process	chemokine-mediated signaling pathway
B	0005125	molecular_function	cytokine activity
B	0005515	molecular_function	protein binding
B	0005576	cellular_component	extracellular region
B	0005615	cellular_component	extracellular space
B	0006935	biological_process	chemotaxis
B	0006954	biological_process	inflammatory response
B	0006955	biological_process	immune response
B	0007154	biological_process	cell communication
B	0007165	biological_process	signal transduction
B	0007267	biological_process	cell-cell signaling
B	0008009	molecular_function	chemokine activity
B	0030335	biological_process	positive regulation of cell migration
B	0048020	molecular_function	CCR chemokine receptor binding
B	0060326	biological_process	cell chemotaxis
B	0061844	biological_process	antimicrobial humoral immune response mediated by antimicrobial peptide
B	0070098	biological_process	chemokine-mediated signaling pathway
C	0005125	molecular_function	cytokine activity
C	0005515	molecular_function	protein binding
C	0005576	cellular_component	extracellular region
C	0005615	cellular_component	extracellular space
C	0006935	biological_process	chemotaxis
C	0006954	biological_process	inflammatory response
C	0006955	biological_process	immune response
C	0007154	biological_process	cell communication
C	0007165	biological_process	signal transduction
C	0007267	biological_process	cell-cell signaling
C	0008009	molecular_function	chemokine activity
C	0030335	biological_process	positive regulation of cell migration
C	0048020	molecular_function	CCR chemokine receptor binding
C	0060326	biological_process	cell chemotaxis
C	0061844	biological_process	antimicrobial humoral immune response mediated by antimicrobial peptide
C	0070098	biological_process	chemokine-mediated signaling pathway
D	0005125	molecular_function	cytokine activity
D	0005515	molecular_function	protein binding
D	0005576	cellular_component	extracellular region
D	0005615	cellular_component	extracellular space
D	0006935	biological_process	chemotaxis
D	0006954	biological_process	inflammatory response
D	0006955	biological_process	immune response
D	0007154	biological_process	cell communication
D	0007165	biological_process	signal transduction
D	0007267	biological_process	cell-cell signaling
D	0008009	molecular_function	chemokine activity
D	0030335	biological_process	positive regulation of cell migration
D	0048020	molecular_function	CCR chemokine receptor binding
D	0060326	biological_process	cell chemotaxis
D	0061844	biological_process	antimicrobial humoral immune response mediated by antimicrobial peptide
D	0070098	biological_process	chemokine-mediated signaling pathway

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE ACT B 101

Chain	Residue
A	SER32
A	PRO33
A	GLN34
B	SER32
B	PRO33
B	GLN34

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Functional Information from PROSITE/UniProt

site_id	PS00472
Number of Residues	42
Details	SMALL_CYTOKINES_CC Small cytokines (intercrine/chemokine) C-C subfamily signature. CCLvytswq..IpqkfIvdYsetspq..Cpkp.GVILltkrgrqi.CA

Chain	Residue	Details
A	CYS11-ALA52

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