Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

4MGG

Crystal structure of an enolase (mandelate racemase subgroup) from labrenzia aggregata iam 12614 (target nysgrc-012903) with bound mg, space group p212121

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000287	molecular_function	magnesium ion binding
A	0003824	molecular_function	catalytic activity
A	0016597	molecular_function	amino acid binding
A	0016829	molecular_function	lyase activity
A	0016836	molecular_function	hydro-lyase activity
A	0016853	molecular_function	isomerase activity
A	0046872	molecular_function	metal ion binding
A	0071230	biological_process	cellular response to amino acid stimulus
A	1901605	biological_process	alpha-amino acid metabolic process
B	0000287	molecular_function	magnesium ion binding
B	0003824	molecular_function	catalytic activity
B	0016597	molecular_function	amino acid binding
B	0016829	molecular_function	lyase activity
B	0016836	molecular_function	hydro-lyase activity
B	0016853	molecular_function	isomerase activity
B	0046872	molecular_function	metal ion binding
B	0071230	biological_process	cellular response to amino acid stimulus
B	1901605	biological_process	alpha-amino acid metabolic process
C	0000287	molecular_function	magnesium ion binding
C	0003824	molecular_function	catalytic activity
C	0016597	molecular_function	amino acid binding
C	0016829	molecular_function	lyase activity
C	0016836	molecular_function	hydro-lyase activity
C	0016853	molecular_function	isomerase activity
C	0046872	molecular_function	metal ion binding
C	0071230	biological_process	cellular response to amino acid stimulus
C	1901605	biological_process	alpha-amino acid metabolic process
D	0000287	molecular_function	magnesium ion binding
D	0003824	molecular_function	catalytic activity
D	0016597	molecular_function	amino acid binding
D	0016829	molecular_function	lyase activity
D	0016836	molecular_function	hydro-lyase activity
D	0016853	molecular_function	isomerase activity
D	0046872	molecular_function	metal ion binding
D	0071230	biological_process	cellular response to amino acid stimulus
D	1901605	biological_process	alpha-amino acid metabolic process
E	0000287	molecular_function	magnesium ion binding
E	0003824	molecular_function	catalytic activity
E	0016597	molecular_function	amino acid binding
E	0016829	molecular_function	lyase activity
E	0016836	molecular_function	hydro-lyase activity
E	0016853	molecular_function	isomerase activity
E	0046872	molecular_function	metal ion binding
E	0071230	biological_process	cellular response to amino acid stimulus
E	1901605	biological_process	alpha-amino acid metabolic process
F	0000287	molecular_function	magnesium ion binding
F	0003824	molecular_function	catalytic activity
F	0016597	molecular_function	amino acid binding
F	0016829	molecular_function	lyase activity
F	0016836	molecular_function	hydro-lyase activity
F	0016853	molecular_function	isomerase activity
F	0046872	molecular_function	metal ion binding
F	0071230	biological_process	cellular response to amino acid stimulus
F	1901605	biological_process	alpha-amino acid metabolic process
G	0000287	molecular_function	magnesium ion binding
G	0003824	molecular_function	catalytic activity
G	0016597	molecular_function	amino acid binding
G	0016829	molecular_function	lyase activity
G	0016836	molecular_function	hydro-lyase activity
G	0016853	molecular_function	isomerase activity
G	0046872	molecular_function	metal ion binding
G	0071230	biological_process	cellular response to amino acid stimulus
G	1901605	biological_process	alpha-amino acid metabolic process
H	0000287	molecular_function	magnesium ion binding
H	0003824	molecular_function	catalytic activity
H	0016597	molecular_function	amino acid binding
H	0016829	molecular_function	lyase activity
H	0016836	molecular_function	hydro-lyase activity
H	0016853	molecular_function	isomerase activity
H	0046872	molecular_function	metal ion binding
H	0071230	biological_process	cellular response to amino acid stimulus
H	1901605	biological_process	alpha-amino acid metabolic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL A 401

Chain	Residue
A	LYS45

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE NI A 402

Chain	Residue
A	HIS98
A	HOH501
A	HOH502
G	HIS98
G	HOH501
G	HOH502

site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG A 403

Chain	Residue
A	HOH506
A	HOH507
A	HOH797
E	HOH804
A	GLY197
A	HOH505

site_id	AC4
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MG A 404

Chain	Residue
A	ASP193
A	GLU218
A	ASP241
A	ASN263
A	HOH510
A	HOH511
A	HOH512

site_id	AC5
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MG B 401

Chain	Residue
B	ASP193
B	GLU218
B	ASP241
B	ASN263
B	HOH501
B	HOH721
B	HOH806

site_id	AC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG B 402

Chain	Residue
B	GLY197
B	HOH503
B	HOH504
B	HOH505
B	HOH506
D	HOH503

site_id	AC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL B 403

Chain	Residue
B	ALA143
B	ARG176

site_id	AC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE NI C 401

Chain	Residue
C	HIS98
C	HOH501
C	HOH502
E	HIS98
E	HOH802
E	HOH803

site_id	AC9
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG C 402

Chain	Residue
C	GLY197
C	HOH503
C	HOH504
C	HOH663
C	HOH730
G	HOH506

site_id	BC1
Number of Residues	8
Details	BINDING SITE FOR RESIDUE MG C 403

Chain	Residue
C	ASP193
C	GLU218
C	ASP241
C	ASN263
C	LYS265
C	HOH507
C	HOH508
C	HOH740

site_id	BC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE NI D 401

Chain	Residue
D	HIS98
D	HOH501
H	HIS98
H	HOH501
H	HOH502
H	HOH503

site_id	BC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG D 402

Chain	Residue
C	HOH505
C	HOH506
D	GLY197
D	HOH504
D	HOH505
D	HOH660

site_id	BC4
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MG D 403

Chain	Residue
D	GLN163
D	ASP193
D	GLU218
D	ASP241
D	HOH512
D	HOH525
D	HOH540

site_id	BC5
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MG E 401

Chain	Residue
E	ASN24
E	GLY197
E	HOH805
E	HOH806
E	HOH807
E	HOH1041
H	HOH504

site_id	BC6
Number of Residues	8
Details	BINDING SITE FOR RESIDUE MG E 402

Chain	Residue
E	ASP193
E	GLU218
E	ASP241
E	ASN263
E	LYS265
E	HOH810
E	HOH811
E	HOH812

site_id	BC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG F 401

Chain	Residue
A	HOH504
F	GLY197
F	HOH501
F	HOH502
F	HOH503
F	HOH703

site_id	BC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG F 402

Chain	Residue
F	HOH505
F	HOH707
F	ASP193
F	GLU218
F	ASP241
F	HOH504

site_id	BC9
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG G 401

Chain	Residue
G	ASP193
G	GLU218
G	ASP241
G	HOH507
G	HOH508
G	HOH509

site_id	CC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MG G 402

Chain	Residue
G	GLU157
G	HOH510
G	HOH511
G	HOH512
G	HOH513
G	HOH514
G	HOH664

site_id	CC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG G 403

Chain	Residue
B	HOH507
G	GLY197
G	HOH515
G	HOH516
G	HOH517
G	HOH518

site_id	CC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MG H 401

Chain	Residue
H	ASP193
H	GLU218
H	ASP241
H	LYS265
H	HOH505
H	HOH506
H	HOH507

site_id	CC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG H 402

Chain	Residue
F	HOH506
H	GLY197
H	HOH508
H	HOH509
H	HOH510
H	HOH641

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	16
Details	ACT_SITE: Proton donor/acceptor => ECO:0000305\|PubMed:25608448

Chain	Residue	Details
A	LYS165
E	LYS265
F	LYS165
F	LYS265
G	LYS165
G	LYS265
H	LYS165
H	LYS265
A	LYS265
B	LYS165
B	LYS265
C	LYS165
C	LYS265
D	LYS165
D	LYS265
E	LYS165

site_id	SWS_FT_FI2
Number of Residues	24
Details	BINDING: BINDING => ECO:0000269\|PubMed:25608448, ECO:0007744\|PDB:4MGG

Chain	Residue	Details
A	ASP193
D	ASP193
D	GLU218
D	ASP241
E	ASP193
E	GLU218
E	ASP241
F	ASP193
F	GLU218
F	ASP241
G	ASP193
A	GLU218
G	GLU218
G	ASP241
H	ASP193
H	GLU218
H	ASP241
A	ASP241
B	ASP193
B	GLU218
B	ASP241
C	ASP193
C	GLU218
C	ASP241

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)