4MGG
Crystal structure of an enolase (mandelate racemase subgroup) from labrenzia aggregata iam 12614 (target nysgrc-012903) with bound mg, space group p212121
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0016597 | molecular_function | amino acid binding |
| A | 0016829 | molecular_function | lyase activity |
| A | 0016836 | molecular_function | hydro-lyase activity |
| A | 0016853 | molecular_function | isomerase activity |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0071230 | biological_process | cellular response to amino acid stimulus |
| A | 1901605 | biological_process | alpha-amino acid metabolic process |
| B | 0000287 | molecular_function | magnesium ion binding |
| B | 0016597 | molecular_function | amino acid binding |
| B | 0016829 | molecular_function | lyase activity |
| B | 0016836 | molecular_function | hydro-lyase activity |
| B | 0016853 | molecular_function | isomerase activity |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0071230 | biological_process | cellular response to amino acid stimulus |
| B | 1901605 | biological_process | alpha-amino acid metabolic process |
| C | 0000287 | molecular_function | magnesium ion binding |
| C | 0016597 | molecular_function | amino acid binding |
| C | 0016829 | molecular_function | lyase activity |
| C | 0016836 | molecular_function | hydro-lyase activity |
| C | 0016853 | molecular_function | isomerase activity |
| C | 0046872 | molecular_function | metal ion binding |
| C | 0071230 | biological_process | cellular response to amino acid stimulus |
| C | 1901605 | biological_process | alpha-amino acid metabolic process |
| D | 0000287 | molecular_function | magnesium ion binding |
| D | 0016597 | molecular_function | amino acid binding |
| D | 0016829 | molecular_function | lyase activity |
| D | 0016836 | molecular_function | hydro-lyase activity |
| D | 0016853 | molecular_function | isomerase activity |
| D | 0046872 | molecular_function | metal ion binding |
| D | 0071230 | biological_process | cellular response to amino acid stimulus |
| D | 1901605 | biological_process | alpha-amino acid metabolic process |
| E | 0000287 | molecular_function | magnesium ion binding |
| E | 0016597 | molecular_function | amino acid binding |
| E | 0016829 | molecular_function | lyase activity |
| E | 0016836 | molecular_function | hydro-lyase activity |
| E | 0016853 | molecular_function | isomerase activity |
| E | 0046872 | molecular_function | metal ion binding |
| E | 0071230 | biological_process | cellular response to amino acid stimulus |
| E | 1901605 | biological_process | alpha-amino acid metabolic process |
| F | 0000287 | molecular_function | magnesium ion binding |
| F | 0016597 | molecular_function | amino acid binding |
| F | 0016829 | molecular_function | lyase activity |
| F | 0016836 | molecular_function | hydro-lyase activity |
| F | 0016853 | molecular_function | isomerase activity |
| F | 0046872 | molecular_function | metal ion binding |
| F | 0071230 | biological_process | cellular response to amino acid stimulus |
| F | 1901605 | biological_process | alpha-amino acid metabolic process |
| G | 0000287 | molecular_function | magnesium ion binding |
| G | 0016597 | molecular_function | amino acid binding |
| G | 0016829 | molecular_function | lyase activity |
| G | 0016836 | molecular_function | hydro-lyase activity |
| G | 0016853 | molecular_function | isomerase activity |
| G | 0046872 | molecular_function | metal ion binding |
| G | 0071230 | biological_process | cellular response to amino acid stimulus |
| G | 1901605 | biological_process | alpha-amino acid metabolic process |
| H | 0000287 | molecular_function | magnesium ion binding |
| H | 0016597 | molecular_function | amino acid binding |
| H | 0016829 | molecular_function | lyase activity |
| H | 0016836 | molecular_function | hydro-lyase activity |
| H | 0016853 | molecular_function | isomerase activity |
| H | 0046872 | molecular_function | metal ion binding |
| H | 0071230 | biological_process | cellular response to amino acid stimulus |
| H | 1901605 | biological_process | alpha-amino acid metabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL A 401 |
| Chain | Residue |
| A | LYS45 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NI A 402 |
| Chain | Residue |
| A | HIS98 |
| A | HOH501 |
| A | HOH502 |
| G | HIS98 |
| G | HOH501 |
| G | HOH502 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG A 403 |
| Chain | Residue |
| A | HOH506 |
| A | HOH507 |
| A | HOH797 |
| E | HOH804 |
| A | GLY197 |
| A | HOH505 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MG A 404 |
| Chain | Residue |
| A | ASP193 |
| A | GLU218 |
| A | ASP241 |
| A | ASN263 |
| A | HOH510 |
| A | HOH511 |
| A | HOH512 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MG B 401 |
| Chain | Residue |
| B | ASP193 |
| B | GLU218 |
| B | ASP241 |
| B | ASN263 |
| B | HOH501 |
| B | HOH721 |
| B | HOH806 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG B 402 |
| Chain | Residue |
| B | GLY197 |
| B | HOH503 |
| B | HOH504 |
| B | HOH505 |
| B | HOH506 |
| D | HOH503 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL B 403 |
| Chain | Residue |
| B | ALA143 |
| B | ARG176 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NI C 401 |
| Chain | Residue |
| C | HIS98 |
| C | HOH501 |
| C | HOH502 |
| E | HIS98 |
| E | HOH802 |
| E | HOH803 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG C 402 |
| Chain | Residue |
| C | GLY197 |
| C | HOH503 |
| C | HOH504 |
| C | HOH663 |
| C | HOH730 |
| G | HOH506 |
| site_id | BC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE MG C 403 |
| Chain | Residue |
| C | ASP193 |
| C | GLU218 |
| C | ASP241 |
| C | ASN263 |
| C | LYS265 |
| C | HOH507 |
| C | HOH508 |
| C | HOH740 |
| site_id | BC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NI D 401 |
| Chain | Residue |
| D | HIS98 |
| D | HOH501 |
| H | HIS98 |
| H | HOH501 |
| H | HOH502 |
| H | HOH503 |
| site_id | BC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG D 402 |
| Chain | Residue |
| C | HOH505 |
| C | HOH506 |
| D | GLY197 |
| D | HOH504 |
| D | HOH505 |
| D | HOH660 |
| site_id | BC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MG D 403 |
| Chain | Residue |
| D | GLN163 |
| D | ASP193 |
| D | GLU218 |
| D | ASP241 |
| D | HOH512 |
| D | HOH525 |
| D | HOH540 |
| site_id | BC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MG E 401 |
| Chain | Residue |
| E | ASN24 |
| E | GLY197 |
| E | HOH805 |
| E | HOH806 |
| E | HOH807 |
| E | HOH1041 |
| H | HOH504 |
| site_id | BC6 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE MG E 402 |
| Chain | Residue |
| E | ASP193 |
| E | GLU218 |
| E | ASP241 |
| E | ASN263 |
| E | LYS265 |
| E | HOH810 |
| E | HOH811 |
| E | HOH812 |
| site_id | BC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG F 401 |
| Chain | Residue |
| A | HOH504 |
| F | GLY197 |
| F | HOH501 |
| F | HOH502 |
| F | HOH503 |
| F | HOH703 |
| site_id | BC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG F 402 |
| Chain | Residue |
| F | HOH505 |
| F | HOH707 |
| F | ASP193 |
| F | GLU218 |
| F | ASP241 |
| F | HOH504 |
| site_id | BC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG G 401 |
| Chain | Residue |
| G | ASP193 |
| G | GLU218 |
| G | ASP241 |
| G | HOH507 |
| G | HOH508 |
| G | HOH509 |
| site_id | CC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MG G 402 |
| Chain | Residue |
| G | GLU157 |
| G | HOH510 |
| G | HOH511 |
| G | HOH512 |
| G | HOH513 |
| G | HOH514 |
| G | HOH664 |
| site_id | CC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG G 403 |
| Chain | Residue |
| B | HOH507 |
| G | GLY197 |
| G | HOH515 |
| G | HOH516 |
| G | HOH517 |
| G | HOH518 |
| site_id | CC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MG H 401 |
| Chain | Residue |
| H | ASP193 |
| H | GLU218 |
| H | ASP241 |
| H | LYS265 |
| H | HOH505 |
| H | HOH506 |
| H | HOH507 |
| site_id | CC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG H 402 |
| Chain | Residue |
| F | HOH506 |
| H | GLY197 |
| H | HOH508 |
| H | HOH509 |
| H | HOH510 |
| H | HOH641 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 16 |
| Details | Active site: {"description":"Proton donor/acceptor","evidences":[{"source":"PubMed","id":"25608448","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 24 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"25608448","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4MGG","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
