4MFD
Structure of the carboxyl transferase domain from Rhizobium etli pyruvate carboxylase with oxalate
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN A 1101 |
| Chain | Residue |
| A | ASP549 |
| A | KCX718 |
| A | HIS747 |
| A | HIS749 |
| A | HOH1286 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE OXL A 1102 |
| Chain | Residue |
| A | LEU619 |
| A | ARG621 |
| A | THR882 |
| A | HOH1279 |
| A | HOH1286 |
| A | ARG548 |
| A | GLN552 |
| A | GLY586 |
| A | ALA587 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG A 1103 |
| Chain | Residue |
| A | MET534 |
| A | ARG535 |
| A | GLU537 |
| A | ASP768 |
| A | HOH1247 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 1104 |
| Chain | Residue |
| A | TYR987 |
| A | PRO988 |
| A | LYS989 |
| A | VAL990 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 1105 |
| Chain | Residue |
| A | ASP750 |
| A | GLY779 |
| A | ASN780 |
| C | ASP750 |
| C | GLY753 |
| C | ASN780 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ZN B 1101 |
| Chain | Residue |
| B | ASP549 |
| B | KCX718 |
| B | HIS747 |
| B | HIS749 |
| B | GLN783 |
| B | HOH1246 |
| site_id | AC7 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE OXL B 1102 |
| Chain | Residue |
| B | ARG548 |
| B | GLN552 |
| B | GLY586 |
| B | ALA587 |
| B | LEU619 |
| B | ARG621 |
| B | KCX718 |
| B | THR882 |
| B | HOH1246 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG B 1103 |
| Chain | Residue |
| B | MET534 |
| B | ARG535 |
| B | GLU537 |
| B | ASP768 |
| B | HOH1228 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL B 1104 |
| Chain | Residue |
| B | TYR987 |
| B | LYS989 |
| B | VAL990 |
| site_id | BC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL B 1105 |
| Chain | Residue |
| B | ASP750 |
| B | GLY753 |
| B | GLY779 |
| B | ASN780 |
| D | ASP750 |
| D | GLY779 |
| D | ASN780 |
| site_id | BC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN C 1101 |
| Chain | Residue |
| C | ASP549 |
| C | KCX718 |
| C | HIS747 |
| C | HIS749 |
| site_id | BC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE OXL C 1102 |
| Chain | Residue |
| C | ARG548 |
| C | ASP549 |
| C | GLN552 |
| C | GLY586 |
| C | ALA587 |
| C | LEU619 |
| C | ARG621 |
| C | THR882 |
| site_id | BC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG C 1103 |
| Chain | Residue |
| C | MET534 |
| C | ARG535 |
| C | GLU537 |
| C | ASP768 |
| C | HOH1223 |
| site_id | BC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL C 1104 |
| Chain | Residue |
| C | TYR987 |
| C | PRO988 |
| C | LYS989 |
| C | VAL990 |
| site_id | BC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ZN D 1101 |
| Chain | Residue |
| D | ASP549 |
| D | KCX718 |
| D | HIS747 |
| D | HIS749 |
| D | GLN783 |
| D | HOH1223 |
| site_id | BC7 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE OXL D 1102 |
| Chain | Residue |
| D | ARG548 |
| D | GLN552 |
| D | ALA587 |
| D | LEU619 |
| D | ARG621 |
| D | KCX718 |
| D | THR882 |
| D | HOH1223 |
| site_id | BC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG D 1103 |
| Chain | Residue |
| D | HOH1213 |
| D | MET534 |
| D | ARG535 |
| D | GLU537 |
| D | ASP768 |
| D | ARG798 |
| site_id | BC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL D 1104 |
| Chain | Residue |
| D | TYR987 |
| D | PRO988 |
| D | LYS989 |
| D | VAL990 |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 6 |
| Details | M-CSA 223 |
| Chain | Residue | Details |
| A | ASP549 | hydrogen bond acceptor, hydrogen bond donor, metal ligand, proton acceptor, proton donor |
| A | ASP655 | activator, metal ligand |
| A | KCX718 | electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| A | THR751 | metal ligand |
| A | GLY753 | metal ligand |
| A | LYS886 | proton acceptor, proton donor, proton relay |
| site_id | MCSA2 |
| Number of Residues | 6 |
| Details | M-CSA 223 |
| Chain | Residue | Details |
| B | ASP549 | hydrogen bond acceptor, hydrogen bond donor, metal ligand, proton acceptor, proton donor |
| B | ASP655 | activator, metal ligand |
| B | KCX718 | electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| B | THR751 | metal ligand |
| B | GLY753 | metal ligand |
| B | LYS886 | proton acceptor, proton donor, proton relay |
| site_id | MCSA3 |
| Number of Residues | 6 |
| Details | M-CSA 223 |
| Chain | Residue | Details |
| C | ASP549 | hydrogen bond acceptor, hydrogen bond donor, metal ligand, proton acceptor, proton donor |
| C | ASP655 | activator, metal ligand |
| C | KCX718 | electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| C | THR751 | metal ligand |
| C | GLY753 | metal ligand |
| C | LYS886 | proton acceptor, proton donor, proton relay |
| site_id | MCSA4 |
| Number of Residues | 6 |
| Details | M-CSA 223 |
| Chain | Residue | Details |
| D | ASP549 | hydrogen bond acceptor, hydrogen bond donor, metal ligand, proton acceptor, proton donor |
| D | ASP655 | activator, metal ligand |
| D | KCX718 | electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| D | THR751 | metal ligand |
| D | GLY753 | metal ligand |
| D | LYS886 | proton acceptor, proton donor, proton relay |
