Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0001786 | molecular_function | phosphatidylserine binding |
| A | 0005509 | molecular_function | calcium ion binding |
| A | 0005544 | molecular_function | calcium-dependent phospholipid binding |
| A | 0005576 | cellular_component | extracellular region |
| A | 0005634 | cellular_component | nucleus |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0007292 | biological_process | female gamete generation |
| A | 0012506 | cellular_component | vesicle membrane |
| A | 0016020 | cellular_component | membrane |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0042803 | molecular_function | protein homodimerization activity |
| A | 0043657 | cellular_component | host cell |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0061025 | biological_process | membrane fusion |
| A | 0070062 | cellular_component | extracellular exosome |
| B | 0001786 | molecular_function | phosphatidylserine binding |
| B | 0005509 | molecular_function | calcium ion binding |
| B | 0005544 | molecular_function | calcium-dependent phospholipid binding |
| B | 0005576 | cellular_component | extracellular region |
| B | 0005634 | cellular_component | nucleus |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0007292 | biological_process | female gamete generation |
| B | 0012506 | cellular_component | vesicle membrane |
| B | 0016020 | cellular_component | membrane |
| B | 0042802 | molecular_function | identical protein binding |
| B | 0042803 | molecular_function | protein homodimerization activity |
| B | 0043657 | cellular_component | host cell |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0061025 | biological_process | membrane fusion |
| B | 0070062 | cellular_component | extracellular exosome |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 401 |
| Chain | Residue |
| A | MET49 |
| A | GLY51 |
| A | GLY53 |
| A | THR54 |
| A | ASP93 |
| A | HOH540 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA A 402 |
| Chain | Residue |
| A | GLU173 |
| A | HOH538 |
| A | MET121 |
| A | GLY123 |
| A | GLY125 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CA A 403 |
| Chain | Residue |
| A | LYS171 |
| A | THR174 |
| A | GLU179 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CA A 404 |
| Chain | Residue |
| A | MET302 |
| A | GLY304 |
| A | LEU305 |
| A | ASP346 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CA A 405 |
| Chain | Residue |
| A | GLY306 |
| A | ASP346 |
| A | HOH506 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CA A 406 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CA B 401 |
| Chain | Residue |
| A | ASP128 |
| A | ASP275 |
| A | HOH502 |
| A | HOH519 |
| A | HOH552 |
| B | ASP275 |
| B | CA405 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA B 402 |
| Chain | Residue |
| B | MET49 |
| B | GLY51 |
| B | GLY53 |
| B | ASP93 |
| B | HOH552 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA B 403 |
| Chain | Residue |
| A | HOH556 |
| B | MET121 |
| B | GLY123 |
| B | GLY125 |
| B | GLU173 |
| site_id | BC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA B 404 |
| Chain | Residue |
| B | LYS171 |
| B | THR174 |
| B | GLU179 |
| B | HOH535 |
| B | HOH550 |
| site_id | BC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA B 405 |
| Chain | Residue |
| A | ASP275 |
| B | ASP128 |
| B | ASP275 |
| B | CA401 |
| B | HOH501 |
| B | HOH533 |
| site_id | BC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CA B 406 |
| Chain | Residue |
| B | MET302 |
| B | ASP346 |
| site_id | BC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CA B 407 |
| Chain | Residue |
| B | GLY306 |
| B | ASP309 |
| B | ASP346 |
Functional Information from PROSITE/UniProt
| site_id | PS00223 |
| Number of Residues | 53 |
| Details | ANNEXIN_1 Annexin repeat signature. GTnelaiiniLarRtnyErqEicqsYkslykqdLkddLksdtsGdfrkvLcqL |
| Chain | Residue | Details |
| A | GLY53-LEU105 | |
| A | GLY231-VAL283 | |
| A | GLY306-LEU358 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 142 |
| Details | Repeat: {"description":"Annexin 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU01245","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 158 |
| Details | Repeat: {"description":"Annexin 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU01245","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 142 |
| Details | Repeat: {"description":"Annexin 4","evidences":[{"source":"PROSITE-ProRule","id":"PRU01245","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 40 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"24428567","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4MDV","evidenceCode":"ECO:0007744"}]} |
