4MA5
The crystal structure of phosphoribosylaminoimidazole carboxylase ATPase subunit of Francisella tularensis subsp. tularensis SCHU S4 in complex with an ATP analog, AMP-PNP.
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004638 | molecular_function | phosphoribosylaminoimidazole carboxylase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005829 | cellular_component | cytosol |
| A | 0006164 | biological_process | purine nucleotide biosynthetic process |
| A | 0006189 | biological_process | 'de novo' IMP biosynthetic process |
| A | 0016829 | molecular_function | lyase activity |
| A | 0016874 | molecular_function | ligase activity |
| A | 0034028 | molecular_function | 5-(carboxyamino)imidazole ribonucleotide synthase activity |
| A | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE FMT A 402 |
| Chain | Residue |
| A | LEU121 |
| A | GLN125 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE NA A 403 |
| Chain | Residue |
| A | GLU37 |
| A | VAL40 |
| A | HOH605 |
| A | HOH630 |
| A | HOH630 |
| A | HOH662 |
| A | HOH662 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA A 404 |
| Chain | Residue |
| A | SER95 |
| A | GLU101 |
| A | GLU259 |
| A | ILE260 |
| A | HOH607 |
| A | HOH666 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 405 |
| Chain | Residue |
| A | ILE272 |
| A | ALA275 |
| A | VAL276 |
| A | THR277 |
| A | SER278 |
| A | GLU281 |
| A | HOH546 |
