4MA0
The crystal structure of phosphoribosylaminoimidazole carboxylase ATPase subunit of Francisella tularensis subsp. tularensis SCHU S4 in complex with partially hydrolysed ATP
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004638 | molecular_function | phosphoribosylaminoimidazole carboxylase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005829 | cellular_component | cytosol |
| A | 0006164 | biological_process | purine nucleotide biosynthetic process |
| A | 0006189 | biological_process | 'de novo' IMP biosynthetic process |
| A | 0016829 | molecular_function | lyase activity |
| A | 0016874 | molecular_function | ligase activity |
| A | 0034028 | molecular_function | 5-(carboxyamino)imidazole ribonucleotide synthase activity |
| A | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE AMP A 401 |
| Chain | Residue |
| A | ARG98 |
| A | GLU183 |
| A | HIS206 |
| A | GLU259 |
| A | PO4402 |
| A | HOH659 |
| A | ILE136 |
| A | LYS138 |
| A | GLY146 |
| A | GLN149 |
| A | GLU175 |
| A | ALA176 |
| A | PHE177 |
| A | VAL178 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PO4 A 402 |
| Chain | Residue |
| A | ASP145 |
| A | GLU247 |
| A | GLU259 |
| A | AMP401 |
| A | HOH526 |
| A | HOH659 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 403 |
| Chain | Residue |
| A | ILE272 |
| A | ALA275 |
| A | THR277 |
| A | SER278 |
| A | GLU281 |
| A | HOH600 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE PEG A 404 |
| Chain | Residue |
| A | GLU215 |
| A | LYS299 |
