4M9U

The crystal structure of phosphoribosylaminoimidazole carboxylase ATPase subunit of Francisella tularensis subsp. tularensis SCHU S4

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0004638	molecular_function	phosphoribosylaminoimidazole carboxylase activity
A	0005524	molecular_function	ATP binding
A	0005829	cellular_component	cytosol
A	0006164	biological_process	purine nucleotide biosynthetic process
A	0006189	biological_process	'de novo' IMP biosynthetic process
A	0016829	molecular_function	lyase activity
A	0016874	molecular_function	ligase activity
A	0034028	molecular_function	5-(carboxyamino)imidazole ribonucleotide synthase activity
A	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE NA A 401

Chain	Residue
A	GLU37
A	VAL40
A	HOH501
A	HOH501
A	HOH550
A	HOH729

---

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE NA A 402

Chain	Residue
A	HOH604
A	HOH683
A	SER95
A	GLU101
A	ILE260

---

site_id	AC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CL A 403

Chain	Residue
A	CYS35

---

site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE ACT A 404

Chain	Residue
A	ALA18
A	SER278
A	HOH503
A	HOH525
A	HOH580
A	HOH609

---

site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ACT A 405

Chain	Residue
A	PHE150
A	VAL151
A	LYS357
A	HOH658

---

site_id	AC6
Number of Residues	8
Details	BINDING SITE FOR RESIDUE ACT A 406

Chain	Residue
A	LYS2
A	LYS232
A	ILE233
A	LYS236
A	HOH561
A	HOH700
A	HOH755
A	HOH803

---

site_id	AC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE ACT A 407

Chain	Residue
A	GLY30
A	LYS31
A	ASN32
A	VAL43
A	ASP45
A	HOH545

---

site_id	AC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ACT A 408

Chain	Residue
A	ILE110
A	ALA111
A	LEU255
A	HOH723

---

site_id	AC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE ACT A 409

Chain	Residue
A	HOH553
A	HOH784

---

site_id	BC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE ACT A 410

Chain	Residue
A	LYS2
A	HIS27
A	GLN60
A	HOH708
A	HOH737
A	HOH758

---

site_id	BC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE ACT A 411

Chain	Residue
A	LYS328
A	HOH567
A	HOH626
A	HOH654
A	HOH655
A	HOH718

---

site_id	BC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ACT A 412

Chain	Residue
A	THR296
A	SER297
A	ARG298
A	HOH689

---

site_id	BC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE ACT A 413

Chain	Residue
A	ASN80
A	SER88
A	ALA89
A	HOH519
A	HOH538
A	HOH774

---

site_id	BC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE FMT A 414

Chain	Residue
A	ARG334

---