4M8J

Crystal structure of CaiT R262E bound to gamma-butyrobetaine

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005886	cellular_component	plasma membrane
A	0009437	biological_process	carnitine metabolic process
A	0015297	molecular_function	antiporter activity
A	0016020	cellular_component	membrane
A	0022857	molecular_function	transmembrane transporter activity
A	0044667	molecular_function	(R)-carnitine:4-(trimethylammonio)butanoate antiporter activity
A	0071705	biological_process	nitrogen compound transport
A	1900749	biological_process	(R)-carnitine transport
A	1900751	biological_process	4-(trimethylammonio)butanoate transport
A	1902270	biological_process	(R)-carnitine transmembrane transport
A	1902603	biological_process	carnitine transmembrane transport

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE NM2 A 601

Chain	Residue
A	SER98
A	TRP147
A	TRP323
A	TRP324
A	TYR327

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Functional Information from PROSITE/UniProt

site_id	PS01303
Number of Residues	10
Details	BCCT BCCT family of transporters signature. AWTVfYWaWW

Chain	Residue	Details
A	ALA315-TRP324

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	272
Details	Transmembrane: {"description":"Helical","evidences":[{"source":"PubMed","id":"20829798","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2WSW","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	112
Details	Topological domain: {"description":"Periplasmic","evidences":[{"source":"PubMed","id":"20829798","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2WSW","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	74
Details	Topological domain: {"description":"Cytoplasmic","evidences":[{"source":"PubMed","id":"20829798","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2WSW","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	1
Details	Site: {"description":"Important for substrate binding and transport mechanism","evidences":[{"source":"PubMed","id":"24101465","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

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