4M87
Crystal Structure of Enoyl-Acyl Carrier Protein Reductase (FabI) from Neisseria meningitidis in complex with NAD+
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0000166 | molecular_function | nucleotide binding |
A | 0004318 | molecular_function | enoyl-[acyl-carrier-protein] reductase (NADH) activity |
A | 0006633 | biological_process | fatty acid biosynthetic process |
A | 0016491 | molecular_function | oxidoreductase activity |
B | 0000166 | molecular_function | nucleotide binding |
B | 0004318 | molecular_function | enoyl-[acyl-carrier-protein] reductase (NADH) activity |
B | 0006633 | biological_process | fatty acid biosynthetic process |
B | 0016491 | molecular_function | oxidoreductase activity |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 30 |
Details | BINDING SITE FOR RESIDUE NAD A 301 |
Chain | Residue |
A | GLY13 |
A | ILE92 |
A | GLY93 |
A | ILE119 |
A | LEU145 |
A | SER146 |
A | LYS164 |
A | ALA190 |
A | GLY191 |
A | PRO192 |
A | ILE193 |
A | ILE15 |
A | THR195 |
A | LEU196 |
A | ALA197 |
A | HOH401 |
A | HOH404 |
A | HOH413 |
A | HOH426 |
A | HOH433 |
A | HOH434 |
A | HOH504 |
A | SER19 |
A | HOH533 |
A | ILE20 |
A | VAL40 |
A | CYS63 |
A | ASP64 |
A | VAL65 |
A | SER91 |
site_id | AC2 |
Number of Residues | 26 |
Details | BINDING SITE FOR RESIDUE NAD B 301 |
Chain | Residue |
B | GLY13 |
B | ILE15 |
B | SER19 |
B | ILE20 |
B | VAL40 |
B | CYS63 |
B | ASP64 |
B | VAL65 |
B | SER91 |
B | ILE92 |
B | GLY93 |
B | ILE119 |
B | LEU145 |
B | SER146 |
B | TYR147 |
B | LYS164 |
B | ALA190 |
B | GLY191 |
B | PRO192 |
B | ILE193 |
B | HOH411 |
B | HOH418 |
B | HOH422 |
B | HOH460 |
B | HOH475 |
B | HOH514 |