4M6M
Crystal structure of anti-IL-23 antibody CNTO1959 at pH 9.5
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL L 301 |
| Chain | Residue |
| L | GLN39 |
| L | LYS47 |
| L | PHE64 |
| L | GLU83 |
| L | ASP84 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE MLA L 302 |
| Chain | Residue |
| L | ASN174 |
| L | HOH415 |
| L | HOH431 |
| L | HOH446 |
| H | TRP99 |
| L | TYR33 |
| L | TRP93 |
| L | GLN113 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PEG H 301 |
| Chain | Residue |
| H | LYS12 |
| H | LYS13 |
| H | GLU16 |
| H | ASN31 |
| H | HOH523 |
Functional Information from PROSITE/UniProt
| site_id | PS00290 |
| Number of Residues | 7 |
| Details | IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YSCQVTH |
| Chain | Residue | Details |
| L | TYR196-HIS202 | |
| H | TYR198-HIS204 |
